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Structural and functional consequences of the STAT5BN642H driver mutation.
de Araujo ED, Erdogan F, Neubauer HA, Meneksedag-Erol D, Manaswiyoungkul P, Eram MS, Seo HS, Qadree AK, Israelian J, Orlova A, Suske T, Pham HTT, Boersma A, Tangermann S, Kenner L, Rülicke T, Dong A, Ravichandran M, Brown PJ, Audette GF, Rauscher S, Dhe-Paganon S, Moriggl R, Gunning PT. de Araujo ED, et al. Among authors: rulicke t. Nat Commun. 2019 Jun 7;10(1):2517. doi: 10.1038/s41467-019-10422-7. Nat Commun. 2019. PMID: 31175292 Free PMC article.
A mouse model to identify cooperating signaling pathways in cancer.
Musteanu M, Blaas L, Zenz R, Svinka J, Hoffmann T, Grabner B, Schramek D, Kantner HP, Müller M, Kolbe T, Rülicke T, Moriggl R, Kenner L, Stoiber D, Penninger JM, Popper H, Casanova E, Eferl R. Musteanu M, et al. Among authors: rulicke t. Nat Methods. 2012 Sep;9(9):897-900. doi: 10.1038/nmeth.2130. Epub 2012 Aug 5. Nat Methods. 2012. PMID: 22863881
Activated STAT5 confers resistance to intestinal injury by increasing intestinal stem cell proliferation and regeneration.
Gilbert S, Nivarthi H, Mayhew CN, Lo YH, Noah TK, Vallance J, Rülicke T, Müller M, Jegga AG, Tang W, Zhang D, Helmrath M, Shroyer N, Moriggl R, Han X. Gilbert S, et al. Among authors: rulicke t. Stem Cell Reports. 2015 Feb 10;4(2):209-25. doi: 10.1016/j.stemcr.2014.12.004. Epub 2015 Jan 8. Stem Cell Reports. 2015. PMID: 25579133 Free PMC article.
STAT5BN642H is a driver mutation for T cell neoplasia.
Pham HTT, Maurer B, Prchal-Murphy M, Grausenburger R, Grundschober E, Javaheri T, Nivarthi H, Boersma A, Kolbe T, Elabd M, Halbritter F, Pencik J, Kazemi Z, Grebien F, Hengstschläger M, Kenner L, Kubicek S, Farlik M, Bock C, Valent P, Müller M, Rülicke T, Sexl V, Moriggl R. Pham HTT, et al. Among authors: rulicke t. J Clin Invest. 2018 Jan 2;128(1):387-401. doi: 10.1172/JCI94509. Epub 2017 Dec 4. J Clin Invest. 2018. PMID: 29200404 Free PMC article.
High activation of STAT5A drives peripheral T-cell lymphoma and leukemia.
Maurer B, Nivarthi H, Wingelhofer B, Pham HTT, Schlederer M, Suske T, Grausenburger R, Schiefer AI, Prchal-Murphy M, Chen D, Winkler S, Merkel O, Kornauth C, Hofbauer M, Hochgatterer B, Hoermann G, Hoelbl-Kovacic A, Prochazkova J, Lobello C, Cumaraswamy AA, Latzka J, Kitzwögerer M, Chott A, Janikova A, Pospíšilova Š, Loizou JI, Kubicek S, Valent P, Kolbe T, Grebien F, Kenner L, Gunning PT, Kralovics R, Herling M, Müller M, Rülicke T, Sexl V, Moriggl R. Maurer B, et al. Among authors: rulicke t. Haematologica. 2020 Jan 31;105(2):435-447. doi: 10.3324/haematol.2019.216986. Print 2020. Haematologica. 2020. PMID: 31123029 Free PMC article.
A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia.
Klein K, Kollmann S, Hiesinger A, List J, Kendler J, Klampfl T, Randhawa M, Trifinopoulos J, Maurer B, Grausenburger R, Bertram CA, Moriggl RH, Rülicke T, Mullighan CG, Witalisz-Siepracka A, Walter W, Hoermann G, Sexl V, Gotthardt D. Klein K, et al. Among authors: rulicke t. Blood. 2024 Mar 18:blood.2023022655. doi: 10.1182/blood.2023022655. Online ahead of print. Blood. 2024. PMID: 38498036 Free article.
220 results