Rüegg C - Search Results

1

mTORC1/autophagy-regulated MerTK in mutant BRAFV600 melanoma with acquired resistance to BRAF inhibition.

Xue G, Kohler R, Tang F, Hynx D, Wang Y, Orso F, Prêtre V, Ritschard R, Hirschmann P, Cron P, Roloff T, Dummer R, Mandalà M, Bichet S, Genoud C, Meyer AG, Muraro MG, Spagnoli GC, Taverna D, Rüegg C, Merghoub T, Massi D, Tang H, Levesque MP, Dirnhofer S, Zippelius A, Hemmings BA, Wicki A. Xue G, et al. Among authors: ruegg c. Oncotarget. 2017 May 25;8(41):69204-69218. doi: 10.18632/oncotarget.18213. eCollection 2017 Sep 19. Oncotarget. 2017. PMID: 29050198 Free PMC article.

2

Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-β signaling axes.

Xue G, Restuccia DF, Lan Q, Hynx D, Dirnhofer S, Hess D, Rüegg C, Hemmings BA. Xue G, et al. Among authors: ruegg c. Cancer Discov. 2012 Mar;2(3):248-59. doi: 10.1158/2159-8290.CD-11-0270. Epub 2012 Jan 25. Cancer Discov. 2012. PMID: 22585995

3

PKB/Akt-dependent regulation of inflammation in cancer.

Tang F, Wang Y, Hemmings BA, Rüegg C, Xue G. Tang F, et al. Among authors: ruegg c. Semin Cancer Biol. 2018 Feb;48:62-69. doi: 10.1016/j.semcancer.2017.04.018. Epub 2017 May 2. Semin Cancer Biol. 2018. PMID: 28476657 Review.

4

The matricellular protein CYR61 interferes with normal pancreatic islets architecture and promotes pancreatic neuroendocrine tumor progression.

Huang YT, Lan Q, Ponsonnet L, Blanquet M, Christofori G, Zaric J, Rüegg C. Huang YT, et al. Among authors: ruegg c. Oncotarget. 2016 Jan 12;7(2):1663-74. doi: 10.18632/oncotarget.6411. Oncotarget. 2016. PMID: 26625209 Free PMC article.

5

The matricellular protein CYR61 promotes breast cancer lung metastasis by facilitating tumor cell extravasation and suppressing anoikis.

Huang YT, Lan Q, Lorusso G, Duffey N, Rüegg C. Huang YT, et al. Among authors: ruegg c. Oncotarget. 2017 Feb 7;8(6):9200-9215. doi: 10.18632/oncotarget.13677. Oncotarget. 2017. PMID: 27911269 Free PMC article.

6

Fibroblast surface-associated FGF-2 promotes contact-dependent colorectal cancer cell migration and invasion through FGFR-SRC signaling and integrin αvβ5-mediated adhesion.

Knuchel S, Anderle P, Werfelli P, Diamantis E, Rüegg C. Knuchel S, et al. Among authors: ruegg c. Oncotarget. 2015 Jun 10;6(16):14300-17. doi: 10.18632/oncotarget.3883. Oncotarget. 2015. PMID: 25973543 Free PMC article.

7

Bevacizumab specifically decreases elevated levels of circulating KIT+CD11b+ cells and IL-10 in metastatic breast cancer patients.

Cattin S, Fellay B, Pradervand S, Trojan A, Ruhstaller T, Rüegg C, Fürstenberger G. Cattin S, et al. Among authors: ruegg c. Oncotarget. 2016 Mar 8;7(10):11137-50. doi: 10.18632/oncotarget.7097. Oncotarget. 2016. PMID: 26840567 Free PMC article.

8

An immature B cell population from peripheral blood serves as surrogate marker for monitoring tumor angiogenesis and anti-angiogenic therapy in mouse models.

Fagiani E, Bill R, Pisarsky L, Ivanek R, Rüegg C, Christofori G. Fagiani E, et al. Among authors: ruegg c. Angiogenesis. 2015 Jul;18(3):327-45. doi: 10.1007/s10456-015-9470-9. Epub 2015 May 29. Angiogenesis. 2015. PMID: 26021306

9

PI3Kγ activity in leukocytes promotes adipose tissue inflammation and early-onset insulin resistance during obesity.

Breasson L, Becattini B, Sardi C, Molinaro A, Zani F, Marone R, Botindari F, Bousquenaud M, Ruegg C, Wymann MP, Solinas G. Breasson L, et al. Among authors: ruegg c. Sci Signal. 2017 Jul 18;10(488):eaaf2969. doi: 10.1126/scisignal.aaf2969. Sci Signal. 2017. PMID: 28720716

10

Proangiogenic factor PlGF programs CD11b(+) myelomonocytes in breast cancer during differentiation of their hematopoietic progenitors.

Laurent J, Hull EF, Touvrey C, Kuonen F, Lan Q, Lorusso G, Doucey MA, Ciarloni L, Imaizumi N, Alghisi GC, Fagiani E, Zaman K, Stupp R, Shibuya M, Delaloye JF, Christofori G, Ruegg C. Laurent J, et al. Among authors: ruegg c. Cancer Res. 2011 Jun 1;71(11):3781-91. doi: 10.1158/0008-5472.CAN-10-3684. Epub 2011 Apr 20. Cancer Res. 2011. PMID: 21507936

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