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Page 1
Abolishing cAMP sensitivity in HCN2 pacemaker channels induces generalized seizures.
Hammelmann V, Stieglitz MS, Hülle H, Le Meur K, Kass J, Brümmer M, Gruner C, Rötzer RD, Fenske S, Hartmann J, Zott B, Lüthi A, Spahn S, Moser M, Isbrandt D, Ludwig A, Konnerth A, Wahl-Schott C, Biel M. Hammelmann V, et al. Among authors: rotzer rd. JCI Insight. 2019 May 2;4(9):e126418. doi: 10.1172/jci.insight.126418. eCollection 2019 May 2. JCI Insight. 2019. PMID: 31045576 Free PMC article.
cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells.
Fenske S, Hennis K, Rötzer RD, Brox VF, Becirovic E, Scharr A, Gruner C, Ziegler T, Mehlfeld V, Brennan J, Efimov IR, Pauža AG, Moser M, Wotjak CT, Kupatt C, Gönner R, Zhang R, Zhang H, Zong X, Biel M, Wahl-Schott C. Fenske S, et al. Among authors: rotzer rd. Nat Commun. 2020 Nov 3;11(1):5555. doi: 10.1038/s41467-020-19304-9. Nat Commun. 2020. PMID: 33144559 Free PMC article.
Speeding Up the Heart? Traditional and New Perspectives on HCN4 Function.
Hennis K, Rötzer RD, Piantoni C, Biel M, Wahl-Schott C, Fenske S. Hennis K, et al. Among authors: rotzer rd. Front Physiol. 2021 May 27;12:669029. doi: 10.3389/fphys.2021.669029. eCollection 2021. Front Physiol. 2021. PMID: 34122140 Free PMC article. Review.
A gene therapy for inherited blindness using dCas9-VPR-mediated transcriptional activation.
Böhm S, Splith V, Riedmayr LM, Rötzer RD, Gasparoni G, Nordström KJV, Wagner JE, Hinrichsmeyer KS, Walter J, Wahl-Schott C, Fenske S, Biel M, Michalakis S, Becirovic E. Böhm S, et al. Among authors: rotzer rd. Sci Adv. 2020 Aug 19;6(34):eaba5614. doi: 10.1126/sciadv.aba5614. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32875106 Free PMC article.