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ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling.
Hirschenberger M, Lepelley A, Rupp U, Klute S, Hunszinger V, Koepke L, Merold V, Didry-Barca B, Wondany F, Bergner T, Moreau T, Rodero MP, Rösler R, Wiese S, Volpi S, Gattorno M, Papa R, Lynch SA, Haug MG, Houge G, Wigby KM, Sprague J, Lenberg J, Read C, Walther P, Michaelis J, Kirchhoff F, de Oliveira Mann CC, Crow YJ, Sparrer KMJ. Hirschenberger M, et al. Among authors: rosler r. Nat Commun. 2023 Nov 1;14(1):6770. doi: 10.1038/s41467-023-42150-4. Nat Commun. 2023. PMID: 37914730 Free PMC article.
Noncatalytic Bruton's tyrosine kinase activates PLCγ2 variants mediating ibrutinib resistance in human chronic lymphocytic leukemia cells.
Wist M, Meier L, Gutman O, Haas J, Endres S, Zhou Y, Rösler R, Wiese S, Stilgenbauer S, Hobeika E, Henis YI, Gierschik P, Walliser C. Wist M, et al. Among authors: rosler r. J Biol Chem. 2020 Apr 24;295(17):5717-5736. doi: 10.1074/jbc.RA119.011946. Epub 2020 Mar 17. J Biol Chem. 2020. PMID: 32184360 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33516310
The ParaHox gene Cdx4 induces acute erythroid leukemia in mice.
Thoene S, Mandal T, Vegi NM, Quintanilla-Martinez L, Rösler R, Wiese S, Metzeler KH, Herold T, Haferlach T, Döhner K, Döhner H, Schwarzmüller L, Klingmüller U, Buske C, Rawat VPS, Feuring-Buske M. Thoene S, et al. Among authors: rosler r. Blood Adv. 2019 Nov 26;3(22):3729-3739. doi: 10.1182/bloodadvances.2019000761. Blood Adv. 2019. PMID: 31770439 Free PMC article.
MicroRNA-708 is a novel regulator of the Hoxa9 program in myeloid cells.
Schneider E, Pochert N, Ruess C, MacPhee L, Escano L, Miller C, Krowiorz K, Delsing Malmberg E, Heravi-Moussavi A, Lorzadeh A, Ashouri A, Grasedieck S, Sperb N, Kumar Kopparapu P, Iben S, Staffas A, Xiang P, Rösler R, Kanduri M, Larsson E, Fogelstrand L, Döhner H, Döhner K, Wiese S, Hirst M, Keith Humphries R, Palmqvist L, Kuchenbauer F, Rouhi A. Schneider E, et al. Among authors: rosler r. Leukemia. 2020 May;34(5):1253-1265. doi: 10.1038/s41375-019-0651-1. Epub 2019 Nov 25. Leukemia. 2020. PMID: 31768018
A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML.
Bamezai S, Pulikkottil AJ, Yadav T, Vegi NM, Mueller J, Mark J, Mandal T, Feder K, Ihme S, Song C, Rosler R, Wiese S, Hoell JI, Kloetgen A, Karsan A, Kumari A, Wojenski L, Sinha AU, Gonzalez-Menendez I, Quintanilla-Martinez L, Donato E, Trumpp A, Kruse E, Hamperl S, Zou L, Rawat VPS, Buske C. Bamezai S, et al. Among authors: rosler r. Blood. 2023 Jul 6;142(1):90-105. doi: 10.1182/blood.2022018651. Blood. 2023. PMID: 37146239
37 results