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High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells.
Sci Rep. 2023 Apr 24;13(1):6639. doi: 10.1038/s41598-023-33352-3.
Sci Rep. 2023.
PMID: 37095146
Free PMC article.
FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells.
Quist-Løkken I, Andersson-Rusch C, Kastnes MH, Kolos JM, Jatzlau J, Hella H, Olsen OE, Sundan A, Knaus P, Hausch F, Holien T.
Quist-Løkken I, et al.
Cell Commun Signal. 2023 Jan 30;21(1):25. doi: 10.1186/s12964-022-01033-9.
Cell Commun Signal. 2023.
PMID: 36717825
Free PMC article.
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Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides.
Kolos JM, Pomplun S, Jung S, Rieß B, Purder PL, Voll AM, Merz S, Gnatzy M, Geiger TM, Quist-Løkken I, Jatzlau J, Knaus P, Holien T, Bracher A, Meyners C, Czodrowski P, Krewald V, Hausch F.
Kolos JM, et al. Among authors: quist lokken i.
Chem Sci. 2021 Nov 3;12(44):14758-14765. doi: 10.1039/d1sc04638a. eCollection 2021 Nov 17.
Chem Sci. 2021.
PMID: 34820091
Free PMC article.
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