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Glioblastoma scRNA-seq shows treatment-induced, immune-dependent increase in mesenchymal cancer cells and structural variants in distal neural stem cells.
Couturier CP, Nadaf J, Li Z, Baig S, Riva G, Le P, Kloosterman DJ, Monlong J, Nkili Meyong A, Allache R, Degenhard T, Al-Rashid M, Guiot MC, Bourque G, Ragoussis J, Akkari L, Quintana FJ, Petrecca K. Couturier CP, et al. Among authors: quintana fj. Neuro Oncol. 2022 Sep 1;24(9):1494-1508. doi: 10.1093/neuonc/noac085. Neuro Oncol. 2022. PMID: 35416251 Free PMC article.
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39.
Takenaka MC, Gabriely G, Rothhammer V, Mascanfroni ID, Wheeler MA, Chao CC, Gutiérrez-Vázquez C, Kenison J, Tjon EC, Barroso A, Vandeventer T, de Lima KA, Rothweiler S, Mayo L, Ghannam S, Zandee S, Healy L, Sherr D, Farez MF, Prat A, Antel J, Reardon DA, Zhang H, Robson SC, Getz G, Weiner HL, Quintana FJ. Takenaka MC, et al. Among authors: quintana fj. Nat Neurosci. 2019 May;22(5):729-740. doi: 10.1038/s41593-019-0370-y. Epub 2019 Apr 8. Nat Neurosci. 2019. PMID: 30962630 Free PMC article.
MAFG-driven astrocytes promote CNS inflammation.
Wheeler MA, Clark IC, Tjon EC, Li Z, Zandee SEJ, Couturier CP, Watson BR, Scalisi G, Alkwai S, Rothhammer V, Rotem A, Heyman JA, Thaploo S, Sanmarco LM, Ragoussis J, Weitz DA, Petrecca K, Moffitt JR, Becher B, Antel JP, Prat A, Quintana FJ. Wheeler MA, et al. Among authors: quintana fj. Nature. 2020 Feb;578(7796):593-599. doi: 10.1038/s41586-020-1999-0. Epub 2020 Feb 12. Nature. 2020. PMID: 32051591 Free PMC article.
A potential role for AHR in SARS-CoV-2 pathology.
Giovannoni F, Li Z, Garcia CC, Quintana FJ. Giovannoni F, et al. Among authors: quintana fj. Res Sq [Preprint]. 2020 Apr 27:rs.3.rs-25639. doi: 10.21203/rs.3.rs-25639/v1. Res Sq. 2020. PMID: 32702728 Free PMC article. Preprint.
Glial and myeloid heterogeneity in the brain tumour microenvironment.
Andersen BM, Faust Akl C, Wheeler MA, Chiocca EA, Reardon DA, Quintana FJ. Andersen BM, et al. Among authors: quintana fj. Nat Rev Cancer. 2021 Dec;21(12):786-802. doi: 10.1038/s41568-021-00397-3. Epub 2021 Sep 28. Nat Rev Cancer. 2021. PMID: 34584243 Free PMC article. Review.
Role of AHR and HIF-1α in Glioblastoma Metabolism.
Gabriely G, Wheeler MA, Takenaka MC, Quintana FJ. Gabriely G, et al. Among authors: quintana fj. Trends Endocrinol Metab. 2017 Jun;28(6):428-436. doi: 10.1016/j.tem.2017.02.009. Epub 2017 Mar 16. Trends Endocrinol Metab. 2017. PMID: 28318896 Free PMC article. Review.
IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment.
Nirschl CJ, Suárez-Fariñas M, Izar B, Prakadan S, Dannenfelser R, Tirosh I, Liu Y, Zhu Q, Devi KSP, Carroll SL, Chau D, Rezaee M, Kim TG, Huang R, Fuentes-Duculan J, Song-Zhao GX, Gulati N, Lowes MA, King SL, Quintana FJ, Lee YS, Krueger JG, Sarin KY, Yoon CH, Garraway L, Regev A, Shalek AK, Troyanskaya O, Anandasabapathy N. Nirschl CJ, et al. Among authors: quintana fj. Cell. 2017 Jun 29;170(1):127-141.e15. doi: 10.1016/j.cell.2017.06.016. Cell. 2017. PMID: 28666115 Free PMC article.
Role of AHR in the control of GBM-associated myeloid cells.
Gabriely G, Quintana FJ. Gabriely G, et al. Among authors: quintana fj. Semin Cancer Biol. 2020 Aug;64:13-18. doi: 10.1016/j.semcancer.2019.05.014. Epub 2019 May 23. Semin Cancer Biol. 2020. PMID: 31128300 Free PMC article. Review.
Tolerogenic nanoparticles suppress central nervous system inflammation.
Kenison JE, Jhaveri A, Li Z, Khadse N, Tjon E, Tezza S, Nowakowska D, Plasencia A, Stanton VP Jr, Sherr DH, Quintana FJ. Kenison JE, et al. Among authors: quintana fj. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):32017-32028. doi: 10.1073/pnas.2016451117. Epub 2020 Nov 25. Proc Natl Acad Sci U S A. 2020. PMID: 33239445 Free PMC article.
236 results