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RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth.
Umesalma S, Kaemmer CA, Kohlmeyer JL, Letney B, Schab AM, Reilly JA, Sheehy RM, Hagen J, Tiwari N, Zhan F, Leidinger MR, O'Dorisio TM, Dillon J, Merrill RA, Meyerholz DK, Perl AL, Brown BJ, Braun TA, Scott AT, Ginader T, Taghiyev AF, Zamba GK, Howe JR, Strack S, Bellizzi AM, Narla G, Darbro BW, Quelle FW, Quelle DE. Umesalma S, et al. Among authors: quelle fw, quelle de. J Clin Invest. 2019 Mar 4;129(4):1641-1653. doi: 10.1172/JCI123049. eCollection 2019 Mar 4. J Clin Invest. 2019. PMID: 30721156 Free PMC article.
Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function.
Korgaonkar C, Hagen J, Tompkins V, Frazier AA, Allamargot C, Quelle FW, Quelle DE. Korgaonkar C, et al. Among authors: quelle fw, quelle de. Mol Cell Biol. 2005 Feb;25(4):1258-71. doi: 10.1128/MCB.25.4.1258-1271.2005. Mol Cell Biol. 2005. PMID: 15684379 Free PMC article.
The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis.
Muniz VP, Barnes JM, Paliwal S, Zhang X, Tang X, Chen S, Zamba KD, Cullen JJ, Meyerholz DK, Meyers S, Davis JN, Grossman SR, Henry MD, Quelle DE. Muniz VP, et al. Among authors: quelle de. Mol Cancer Res. 2011 Jul;9(7):867-77. doi: 10.1158/1541-7786.MCR-10-0475. Epub 2011 Jun 2. Mol Cancer Res. 2011. PMID: 21636682 Free PMC article.
65 results