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Extracellular AGR2 activates neighboring fibroblasts through endocytosis and direct binding to β-catenin that requires AGR2 dimerization and adhesion domains.
Merugu SB, Zhou B, Mangukiya HB, Negi H, Ghulam R, Roy D, Qudsia S, Wang Z, Mashausi DS, Yunus FU, Liu GS, Li D. Merugu SB, et al. Among authors: qudsia s. Biochem Biophys Res Commun. 2021 Oct 8;573:86-92. doi: 10.1016/j.bbrc.2021.08.028. Epub 2021 Aug 10. Biochem Biophys Res Commun. 2021. PMID: 34399098
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