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CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance.
Quarta C, Bellocchio L, Mancini G, Mazza R, Cervino C, Braulke LJ, Fekete C, Latorre R, Nanni C, Bucci M, Clemens LE, Heldmaier G, Watanabe M, Leste-Lassere T, Maitre M, Tedesco L, Fanelli F, Reuss S, Klaus S, Srivastava RK, Monory K, Valerio A, Grandis A, De Giorgio R, Pasquali R, Nisoli E, Cota D, Lutz B, Marsicano G, Pagotto U. Quarta C, et al. Cell Metab. 2010 Apr 7;11(4):273-85. doi: 10.1016/j.cmet.2010.02.015. Cell Metab. 2010. PMID: 20374960 Free article.
Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB₁ receptor blockade.
Bellocchio L, Soria-Gómez E, Quarta C, Metna-Laurent M, Cardinal P, Binder E, Cannich A, Delamarre A, Häring M, Martín-Fontecha M, Vega D, Leste-Lasserre T, Bartsch D, Monory K, Lutz B, Chaouloff F, Pagotto U, Guzman M, Cota D, Marsicano G. Bellocchio L, et al. Among authors: quarta c. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4786-91. doi: 10.1073/pnas.1218573110. Epub 2013 Mar 4. Proc Natl Acad Sci U S A. 2013. PMID: 23487769 Free PMC article.
CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin.
Cardinal P, André C, Quarta C, Bellocchio L, Clark S, Elie M, Leste-Lasserre T, Maitre M, Gonzales D, Cannich A, Pagotto U, Marsicano G, Cota D. Cardinal P, et al. Among authors: quarta c. Mol Metab. 2014 Aug 1;3(7):705-16. doi: 10.1016/j.molmet.2014.07.004. eCollection 2014 Oct. Mol Metab. 2014. PMID: 25352999 Free PMC article.
Epigenetic ON/OFF Switches for Obesity.
Quarta C, Schneider R, Tschöp MH. Quarta C, et al. Cell. 2016 Jan 28;164(3):341-2. doi: 10.1016/j.cell.2016.01.006. Cell. 2016. PMID: 26824648 Free article.
Hypothalamic leptin action is mediated by histone deacetylase 5.
Kabra DG, Pfuhlmann K, García-Cáceres C, Schriever SC, Casquero García V, Kebede AF, Fuente-Martin E, Trivedi C, Heppner K, Uhlenhaut NH, Legutko B, Kabra UD, Gao Y, Yi CX, Quarta C, Clemmensen C, Finan B, Müller TD, Meyer CW, Paez-Pereda M, Stemmer K, Woods SC, Perez-Tilve D, Schneider R, Olson EN, Tschöp MH, Pfluger PT. Kabra DG, et al. Among authors: quarta c. Nat Commun. 2016 Feb 29;7:10782. doi: 10.1038/ncomms10782. Nat Commun. 2016. PMID: 26923837 Free PMC article.
Renaissance of leptin for obesity therapy.
Quarta C, Sánchez-Garrido MA, Tschöp MH, Clemmensen C. Quarta C, et al. Diabetologia. 2016 May;59(5):920-7. doi: 10.1007/s00125-016-3906-7. Epub 2016 Mar 16. Diabetologia. 2016. PMID: 26983921 Review.
Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability.
García-Cáceres C, Quarta C, Varela L, Gao Y, Gruber T, Legutko B, Jastroch M, Johansson P, Ninkovic J, Yi CX, Le Thuc O, Szigeti-Buck K, Cai W, Meyer CW, Pfluger PT, Fernandez AM, Luquet S, Woods SC, Torres-Alemán I, Kahn CR, Götz M, Horvath TL, Tschöp MH. García-Cáceres C, et al. Among authors: quarta c. Cell. 2016 Aug 11;166(4):867-880. doi: 10.1016/j.cell.2016.07.028. Cell. 2016. PMID: 27518562 Free PMC article.
Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.
Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph SS, Lutter D, Yi CX, Graf E, García-Cáceres C, Legutko B, Fischer K, Brommage R, Zizzari P, Franklin BS, Krueger M, Koch M, Vettorazzi S, Li P, Hofmann SM, Bakhti M, Bastidas-Ponce A, Lickert H, Strom TM, Gailus-Durner V, Bechmann I, Perez-Tilve D, Tuckermann J, Hrabě de Angelis M, Sandoval D, Cota D, Latz E, Seeley RJ, Müller TD, DiMarchi RD, Finan B, Tschöp MH. Quarta C, et al. Cell Metab. 2017 Oct 3;26(4):620-632.e6. doi: 10.1016/j.cmet.2017.08.023. Epub 2017 Sep 21. Cell Metab. 2017. PMID: 28943448 Free article.
Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages.
Ruiz de Azua I, Mancini G, Srivastava RK, Rey AA, Cardinal P, Tedesco L, Zingaretti CM, Sassmann A, Quarta C, Schwitter C, Conrad A, Wettschureck N, Vemuri VK, Makriyannis A, Hartwig J, Mendez-Lago M, Bindila L, Monory K, Giordano A, Cinti S, Marsicano G, Offermanns S, Nisoli E, Pagotto U, Cota D, Lutz B. Ruiz de Azua I, et al. Among authors: quarta c. J Clin Invest. 2017 Nov 1;127(11):4148-4162. doi: 10.1172/JCI83626. Epub 2017 Oct 16. J Clin Invest. 2017. PMID: 29035280 Free PMC article.
148 results