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Mitochondria are required for pro-ageing features of the senescent phenotype.
Correia-Melo C, Marques FD, Anderson R, Hewitt G, Hewitt R, Cole J, Carroll BM, Miwa S, Birch J, Merz A, Rushton MD, Charles M, Jurk D, Tait SW, Czapiewski R, Greaves L, Nelson G, Bohlooly-Y M, Rodriguez-Cuenca S, Vidal-Puig A, Mann D, Saretzki G, Quarato G, Green DR, Adams PD, von Zglinicki T, Korolchuk VI, Passos JF. Correia-Melo C, et al. Among authors: quarato g. EMBO J. 2016 Apr 1;35(7):724-42. doi: 10.15252/embj.201592862. Epub 2016 Feb 4. EMBO J. 2016. PMID: 26848154 Free PMC article.
Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy.
Sano R, Hou YC, Hedvat M, Correa RG, Shu CW, Krajewska M, Diaz PW, Tamble CM, Quarato G, Gottlieb RA, Yamaguchi M, Nizet V, Dahl R, Thomas DD, Tait SW, Green DR, Fisher PB, Matsuzawa S, Reed JC. Sano R, et al. Among authors: quarato g. Genes Dev. 2012 May 15;26(10):1041-54. doi: 10.1101/gad.184325.111. Genes Dev. 2012. PMID: 22588718 Free PMC article.
Widespread mitochondrial depletion via mitophagy does not compromise necroptosis.
Tait SW, Oberst A, Quarato G, Milasta S, Haller M, Wang R, Karvela M, Ichim G, Yatim N, Albert ML, Kidd G, Wakefield R, Frase S, Krautwald S, Linkermann A, Green DR. Tait SW, et al. Among authors: quarato g. Cell Rep. 2013 Nov 27;5(4):878-85. doi: 10.1016/j.celrep.2013.10.034. Epub 2013 Nov 21. Cell Rep. 2013. PMID: 24268776 Free PMC article.
RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3.
Dillon CP, Weinlich R, Rodriguez DA, Cripps JG, Quarato G, Gurung P, Verbist KC, Brewer TL, Llambi F, Gong YN, Janke LJ, Kelliher MA, Kanneganti TD, Green DR. Dillon CP, et al. Among authors: quarato g. Cell. 2014 May 22;157(5):1189-202. doi: 10.1016/j.cell.2014.04.018. Epub 2014 May 8. Cell. 2014. PMID: 24813850 Free PMC article.
Haploinsufficiency of the 22q11.2 microdeletion gene Mrpl40 disrupts short-term synaptic plasticity and working memory through dysregulation of mitochondrial calcium.
Devaraju P, Yu J, Eddins D, Mellado-Lagarde MM, Earls LR, Westmoreland JJ, Quarato G, Green DR, Zakharenko SS. Devaraju P, et al. Among authors: quarato g. Mol Psychiatry. 2017 Sep;22(9):1313-1326. doi: 10.1038/mp.2016.75. Epub 2016 May 17. Mol Psychiatry. 2017. PMID: 27184122 Free PMC article.
Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis.
Riley JS, Quarato G, Cloix C, Lopez J, O'Prey J, Pearson M, Chapman J, Sesaki H, Carlin LM, Passos JF, Wheeler AP, Oberst A, Ryan KM, Tait SW. Riley JS, et al. Among authors: quarato g. EMBO J. 2018 Sep 3;37(17):e99238. doi: 10.15252/embj.201899238. Epub 2018 Jul 26. EMBO J. 2018. PMID: 30049712 Free PMC article.
LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.
Cunha LD, Yang M, Carter R, Guy C, Harris L, Crawford JC, Quarato G, Boada-Romero E, Kalkavan H, Johnson MDL, Natarajan S, Turnis ME, Finkelstein D, Opferman JT, Gawad C, Green DR. Cunha LD, et al. Among authors: quarato g. Cell. 2018 Oct 4;175(2):429-441.e16. doi: 10.1016/j.cell.2018.08.061. Epub 2018 Sep 20. Cell. 2018. PMID: 30245008 Free PMC article.
39 results