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Page 1
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.
Chen F, Wang X, Jang SK, Quach BC, Weissenkampen JD, Khunsriraksakul C, Yang L, Sauteraud R, Albert CM, Allred NDD, Arnett DK, Ashley-Koch AE, Barnes KC, Barr RG, Becker DM, Bielak LF, Bis JC, Blangero J, Boorgula MP, Chasman DI, Chavan S, Chen YI, Chuang LM, Correa A, Curran JE, David SP, Fuentes LL, Deka R, Duggirala R, Faul JD, Garrett ME, Gharib SA, Guo X, Hall ME, Hawley NL, He J, Hobbs BD, Hokanson JE, Hsiung CA, Hwang SJ, Hyde TM, Irvin MR, Jaffe AE, Johnson EO, Kaplan R, Kardia SLR, Kaufman JD, Kelly TN, Kleinman JE, Kooperberg C, Lee IT, Levy D, Lutz SM, Manichaikul AW, Martin LW, Marx O, McGarvey ST, Minster RL, Moll M, Moussa KA, Naseri T, North KE, Oelsner EC, Peralta JM, Peyser PA, Psaty BM, Rafaels N, Raffield LM, Reupena MS, Rich SS, Rotter JI, Schwartz DA, Shadyab AH, Sheu WH, Sims M, Smith JA, Sun X, Taylor KD, Telen MJ, Watson H, Weeks DE, Weir DR, Yanek LR, Young KA, Young KL, Zhao W, Hancock DB, Jiang B, Vrieze S, Liu DJ. Chen F, et al. Among authors: quach bc. Nat Genet. 2023 Feb;55(2):291-300. doi: 10.1038/s41588-022-01282-x. Epub 2023 Jan 26. Nat Genet. 2023. PMID: 36702996 Free PMC article.
Genome-wide DNA methylation differences in nucleus accumbens of smokers vs. nonsmokers.
Markunas CA, Semick SA, Quach BC, Tao R, Deep-Soboslay A, Carnes MU, Bierut LJ, Hyde TM, Kleinman JE, Johnson EO, Jaffe AE, Hancock DB. Markunas CA, et al. Among authors: quach bc. Neuropsychopharmacology. 2021 Feb;46(3):554-560. doi: 10.1038/s41386-020-0782-0. Epub 2020 Jul 30. Neuropsychopharmacology. 2021. PMID: 32731254 Free PMC article.
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits.
Quach BC, Bray MJ, Gaddis NC, Liu M, Palviainen T, Minica CC, Zellers S, Sherva R, Aliev F, Nothnagel M, Young KA, Marks JA, Young H, Carnes MU, Guo Y, Waldrop A, Sey NYA, Landi MT, McNeil DW, Drichel D, Farrer LA, Markunas CA, Vink JM, Hottenga JJ, Iacono WG, Kranzler HR, Saccone NL, Neale MC, Madden P, Rietschel M, Marazita ML, McGue M, Won H, Winterer G, Grucza R, Dick DM, Gelernter J, Caporaso NE, Baker TB, Boomsma DI, Kaprio J, Hokanson JE, Vrieze S, Bierut LJ, Johnson EO, Hancock DB. Quach BC, et al. Nat Commun. 2020 Nov 3;11(1):5562. doi: 10.1038/s41467-020-19265-z. Nat Commun. 2020. PMID: 33144568 Free PMC article.
Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose.
Corradin O, Sallari R, Hoang AT, Kassim BS, Ben Hutta G, Cuoto L, Quach BC, Lovrenert K, Hays C, Gryder BE, Iskhakova M, Cates H, Song Y, Bartels CF, Hancock DB, Mash DC, Johnson EO, Akbarian S, Scacheri PC. Corradin O, et al. Among authors: quach bc. Mol Psychiatry. 2022 Apr;27(4):2158-2170. doi: 10.1038/s41380-022-01477-y. Epub 2022 Mar 17. Mol Psychiatry. 2022. PMID: 35301427 Free PMC article.
Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits.
Sey NYA, Hu B, Iskhakova M, Lee S, Sun H, Shokrian N, Ben Hutta G, Marks JA, Quach BC, Johnson EO, Hancock DB, Akbarian S, Won H. Sey NYA, et al. Among authors: quach bc. Mol Psychiatry. 2022 Jul;27(7):3085-3094. doi: 10.1038/s41380-022-01558-y. Epub 2022 Apr 14. Mol Psychiatry. 2022. PMID: 35422469 Free PMC article.
Correction: Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits.
Sey NYA, Hu B, Iskhakova M, Lee S, Sun H, Shokrian N, Ben Hutta G, Marks JA, Quach BC, Johnson EO, Hancock DB, Akbarian S, Won H. Sey NYA, et al. Among authors: quach bc. Mol Psychiatry. 2022 Oct;27(10):4368. doi: 10.1038/s41380-022-01678-5. Mol Psychiatry. 2022. PMID: 35794187 No abstract available.
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond.
Gaddis N, Mathur R, Marks J, Zhou L, Quach B, Waldrop A, Levran O, Agrawal A, Randesi M, Adelson M, Jeffries PW, Martin NG, Degenhardt L, Montgomery GW, Wetherill L, Lai D, Bucholz K, Foroud T, Porjesz B, Runarsdottir V, Tyrfingsson T, Einarsson G, Gudbjartsson DF, Webb BT, Crist RC, Kranzler HR, Sherva R, Zhou H, Hulse G, Wildenauer D, Kelty E, Attia J, Holliday EG, McEvoy M, Scott RJ, Schwab SG, Maher BS, Gruza R, Kreek MJ, Nelson EC, Thorgeirsson T, Stefansson K, Berrettini WH, Gelernter J, Edenberg HJ, Bierut L, Hancock DB, Johnson EO. Gaddis N, et al. Sci Rep. 2022 Oct 7;12(1):16873. doi: 10.1038/s41598-022-21003-y. Sci Rep. 2022. PMID: 36207451 Free PMC article.
Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci.
Carnes MU, Quach BC, Zhou L, Han S, Tao R, Mandal M, Deep-Soboslay A, Marks JA, Page GP, Maher BS, Jaffe AE, Won H, Bierut LJ, Hyde TM, Kleinman JE, Johnson EO, Hancock DB. Carnes MU, et al. Among authors: quach bc. medRxiv [Preprint]. 2023 Sep 18:2023.09.18.23295431. doi: 10.1101/2023.09.18.23295431. medRxiv. 2023. PMID: 37790540 Free PMC article. Preprint.
17 results