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N-Acetylcysteine overcomes epalrestat-mediated increase of toxic 4-hydroxy-2-nonenal and potentiates the anti-arthritic effect of epalrestat in AIA model.
Wang L, Huang B, Zeng Y, Yang J, Li Z, Ng JPL, Xu X, Su L, Yun X, Qu L, Chen R, Luo W, Wang Y, Chen C, Yang L, Qu Y, Zhang W, Chan JTW, Wang X, Law BYK, Mok SWF, Chung SK, Wong VKW. Wang L, et al. Among authors: qu l, qu y. Int J Biol Sci. 2023 Aug 6;19(13):4082-4102. doi: 10.7150/ijbs.85028. eCollection 2023. Int J Biol Sci. 2023. PMID: 37705749 Free PMC article.
Age-related self-DNA accumulation may accelerate arthritis in rats and in human rheumatoid arthritis.
Luo WD, Wang YP, Lv J, Liu Y, Qu YQ, Xu XF, Yang LJ, Lin ZC, Wang LN, Chen RH, Yang JJ, Zeng YL, Zhang RL, Huang BX, Yun XY, Wang XY, Song LL, Wu JH, Wang XX, Chen X, Zhang W, Wang HM, Qu LQ, Liu MH, Liu L, Law BYK, Wong VKW. Luo WD, et al. Among authors: qu yq, qu lq. Nat Commun. 2023 Jul 20;14(1):4394. doi: 10.1038/s41467-023-40113-3. Nat Commun. 2023. PMID: 37474626 Free PMC article.
Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats.
Wong VKW, Qiu C, Xu SW, Law BYK, Zeng W, Wang H, Michelangeli F, Dias IRSR, Qu YQ, Chan TW, Han Y, Zhang N, Mok SWF, Chen X, Yu L, Pan H, Hamdoun S, Efferth T, Yu WJ, Zhang W, Li Z, Xie Y, Luo R, Jiang Q, Liu L. Wong VKW, et al. Among authors: qu yq. Br J Pharmacol. 2019 Aug;176(16):2922-2944. doi: 10.1111/bph.14718. Epub 2019 Jul 4. Br J Pharmacol. 2019. PMID: 31124139 Free PMC article.
Hyperoside alleviates toxicity of β-amyloid via endoplasmic reticulum-mitochondrial calcium signal transduction cascade in APP/PS1 double transgenic Alzheimer's disease mice.
Song LL, Qu YQ, Tang YP, Chen X, Lo HH, Qu LQ, Yun YX, Wong VKW, Zhang RL, Wang HM, Liu MH, Zhang W, Zhang HX, Chan JTW, Wang CR, Wu JH, Law BYK. Song LL, et al. Redox Biol. 2023 May;61:102637. doi: 10.1016/j.redox.2023.102637. Epub 2023 Feb 14. Redox Biol. 2023. PMID: 36821955 Free PMC article.
6,753 results