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Design, Synthesis, and Characterization of Benzimidazole Derivatives as Positron Emission Tomography Imaging Ligands for Metabotropic Glutamate Receptor 2.
Yuan G, Qu X, Zheng B, Neelamegam R, Afshar S, Iyengar S, Pan C, Wang J, Kang HJ, Ondrechen MJ, Poutiainen P, El Fakhri G, Zhang Z, Brownell AL. Yuan G, et al. Among authors: qu x. J Med Chem. 2020 Oct 22;63(20):12060-12072. doi: 10.1021/acs.jmedchem.0c01394. Epub 2020 Oct 7. J Med Chem. 2020. PMID: 32981322 Free PMC article.
PET imaging studies to investigate functional expression of mGluR2 using [11C]mG2P001.
Yuan G, Dhaynaut M, Guehl NJ, Neelamegam R, Moon SH, Qu X, Poutiainen P, Afshar S, Fakhri GE, Normandin MD, Brownell AL. Yuan G, et al. Among authors: qu x. J Cereb Blood Flow Metab. 2023 Feb;43(2):296-308. doi: 10.1177/0271678X221130387. Epub 2022 Sep 28. J Cereb Blood Flow Metab. 2023. PMID: 36172629 Free PMC article.
Dual blockade of CXCL12-CXCR4 and PD-1-PD-L1 pathways prolongs survival of ovarian tumor-bearing mice by prevention of immunosuppression in the tumor microenvironment.
Zeng Y, Li B, Liang Y, Reeves PM, Qu X, Ran C, Liu Q, Callahan MV, Sluder AE, Gelfand JA, Chen H, Poznansky MC. Zeng Y, et al. Among authors: qu x. FASEB J. 2019 May;33(5):6596-6608. doi: 10.1096/fj.201802067RR. Epub 2019 Feb 25. FASEB J. 2019. PMID: 30802149 Free PMC article.
We found that AMD3100, a highly specific CXCR4 antagonist, directly down-regulated the expression of both C-X-C motif chemokine 12 (CXCL12) and CXCR4 in vitro and in vivo in tumor cells. ...These results suggest that AMD3100 could be used to target the CXCR4-CXCL12 axis to …
We found that AMD3100, a highly specific CXCR4 antagonist, directly down-regulated the expression of both C-X-C motif chemokine 12 (C …
5,441 results