Isorhynchophylline exerts antidepressant-like effects in mice via modulating neuroinflammation and neurotrophins: involvement of the PI3K/Akt/GSK-3β signaling pathway.
Xian YF, Ip SP, Li HQ, Qu C, Su ZR, Chen JN, Lin ZX.
Xian YF, et al. Among authors: qu c.
FASEB J. 2019 Sep;33(9):10393-10408. doi: 10.1096/fj.201802743RR. Epub 2019 Jun 24.
FASEB J. 2019.
PMID: 31233346
The results of mechanistic investigations indicated that the antidepressant-like action of IRN was mediated, at least in part, by enhancing neurotrophins and attenuating neuroinflammation via modulating the PI3K/Akt/GSK-3beta pathway.-Xian, Y.-F., Ip, S.-P., Li, H.-Q., Qu, …
The results of mechanistic investigations indicated that the antidepressant-like action of IRN was mediated, at least in part, by enhancing …