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A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent.
Gioelli N, Maione F, Camillo C, Ghitti M, Valdembri D, Morello N, Darche M, Zentilin L, Cagnoni G, Qiu Y, Giacca M, Giustetto M, Paques M, Cascone I, Musco G, Tamagnone L, Giraudo E, Serini G. Gioelli N, et al. Among authors: qiu y. Sci Transl Med. 2018 May 23;10(442):eaah4807. doi: 10.1126/scitranslmed.aah4807. Sci Transl Med. 2018. PMID: 29794061 Free article.
HIV Protease Inhibitors Block HPV16-Induced Murine Cervical Carcinoma and Promote Vessel Normalization in Association with MMP-9 Inhibition and TIMP-3 Induction.
Qiu Y, Maione F, Capano S, Meda C, Picconi O, Brundu S, Pisacane A, Sapino A, Palladino C, Barillari G, Monini P, Bussolino F, Ensoli B, Sgadari C, Giraudo E. Qiu Y, et al. Mol Cancer Ther. 2020 Dec;19(12):2476-2489. doi: 10.1158/1535-7163.MCT-20-0055. Epub 2020 Oct 20. Mol Cancer Ther. 2020. PMID: 33082275
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Biphenyl Moiety.
Sainas S, Giorgis M, Circosta P, Gaidano V, Bonanni D, Pippione AC, Bagnati R, Passoni A, Qiu Y, Cojocaru CF, Canepa B, Bona A, Rolando B, Mishina M, Ramondetti C, Buccinnà B, Piccinini M, Houshmand M, Cignetti A, Giraudo E, Al-Karadaghi S, Boschi D, Saglio G, Lolli ML. Sainas S, et al. Among authors: qiu y. J Med Chem. 2021 May 13;64(9):5404-5428. doi: 10.1021/acs.jmedchem.0c01549. Epub 2021 Apr 12. J Med Chem. 2021. PMID: 33844533 Free PMC article.
3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFβRII-SMADS pathway.
Wang N, Li X, Zhong Z, Qiu Y, Liu S, Wu H, Tang X, Chen C, Fu Y, Chen Q, Guo T, Li J, Zhang S, Zern MA, Ma K, Wang B, Ou Y, Gu W, Cao J, Chen H, Duan Y. Wang N, et al. Among authors: qiu y. J Nanobiotechnology. 2021 Dec 20;19(1):437. doi: 10.1186/s12951-021-01138-2. J Nanobiotechnology. 2021. PMID: 34930304 Free PMC article.
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