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IL-1β Is an Androgen-Responsive Target in Macrophages for Immunotherapy of Prostate Cancer.
Wang D, Cheng C, Chen X, Wang J, Liu K, Jing N, Xu P, Xi X, Sun Y, Ji Z, Zhao H, He Y, Zhang K, Du X, Dong B, Fang Y, Zhang P, Qian X, Xue W, Gao WQ, Zhu HH. Wang D, et al. Among authors: qian x. Adv Sci (Weinh). 2023 Jun;10(17):e2206889. doi: 10.1002/advs.202206889. Epub 2023 Apr 24. Adv Sci (Weinh). 2023. PMID: 37092583 Free PMC article.
Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer.
Cheng C, Wang J, Xu P, Zhang K, Xin Z, Zhao H, Ji Z, Zhang M, Wang D, He Y, Jing N, Fan L, Liu K, Li F, Liu C, Gong Y, Cui S, Sun Z, Sun D, Yao X, Li H, Zhang J, Zhang P, Dong B, Xue W, Qian X, Gao WQ, Zhu HH. Cheng C, et al. Among authors: qian x. Nat Cancer. 2022 May;3(5):565-580. doi: 10.1038/s43018-022-00380-3. Epub 2022 May 27. Nat Cancer. 2022. PMID: 35624341
Establishment of peripheral blood mononuclear cell-derived humanized lung cancer mouse models for studying efficacy of PD-L1/PD-1 targeted immunotherapy.
Lin S, Huang G, Cheng L, Li Z, Xiao Y, Deng Q, Jiang Y, Li B, Lin S, Wang S, Wu Q, Yao H, Cao S, Li Y, Liu P, Wei W, Pei D, Yao Y, Wen Z, Zhang X, Wu Y, Zhang Z, Cui S, Sun X, Qian X, Li P. Lin S, et al. Among authors: qian x. MAbs. 2018 Nov-Dec;10(8):1301-1311. doi: 10.1080/19420862.2018.1518948. Epub 2018 Oct 2. MAbs. 2018. PMID: 30204048 Free PMC article.
Phase I study of MSB2311, a novel pH-dependent anti-PD-L1 monoclonal antibody, treating patients with advanced solid tumors and lymphoma.
Zhang Q, Zhang J, Zhong H, Yuan Y, Yang L, Zhang Q, Ji D, Gong J, Li J, Yao Z, Qi C, Wang J, Lu L, Shi M, Qian X, Shen L, Li J, Hu X. Zhang Q, et al. Among authors: qian x. Cancer Immunol Immunother. 2023 Aug;72(8):2729-2739. doi: 10.1007/s00262-023-03434-2. Epub 2023 Apr 28. Cancer Immunol Immunother. 2023. PMID: 37115210 Free PMC article. Clinical Trial.
Single shot dendritic cell targeting SARS-CoV-2 vaccine candidate induces broad, durable and protective systemic and mucosal immune responses in mice.
Zhi Cheang NY, Tan KS, Tan PS, Purushotorma K, Yap WC, Tullett KM, Leong Chua BY, Ying-Yan Yeoh A, Hui Tan CQ, Qian X, Chen H, Wen Tay DJ, Caminschi I, Tan YJ, Macary PA, Tan CW, Lahoud MH, Alonso S. Zhi Cheang NY, et al. Among authors: qian x. Mol Ther. 2024 May 6:S1525-0016(24)00304-6. doi: 10.1016/j.ymthe.2024.05.003. Online ahead of print. Mol Ther. 2024. PMID: 38715364
5,549 results