Qi LS - Search Results

1

A versatile CRISPR-Cas13d platform for multiplexed transcriptomic regulation and metabolic engineering in primary human T cells.

Tieu V, Sotillo E, Bjelajac JR, Chen C, Malipatlolla M, Guerrero JA, Xu P, Quinn PJ, Fisher C, Klysz D, Mackall CL, Qi LS. Tieu V, et al. Among authors: qi ls. Cell. 2024 Feb 29;187(5):1278-1295.e20. doi: 10.1016/j.cell.2024.01.035. Epub 2024 Feb 21. Cell. 2024. PMID: 38387457

2

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.

Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA. Qi LS, et al. Cell. 2013 Feb 28;152(5):1173-83. doi: 10.1016/j.cell.2013.02.022. Cell. 2013. PMID: 23452860 Free PMC article.

3

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.

Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS. Gilbert LA, et al. Among authors: qi ls. Cell. 2013 Jul 18;154(2):442-51. doi: 10.1016/j.cell.2013.06.044. Epub 2013 Jul 11. Cell. 2013. PMID: 23849981 Free PMC article.

4

Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system.

Chen B, Gilbert LA, Cimini BA, Schnitzbauer J, Zhang W, Li GW, Park J, Blackburn EH, Weissman JS, Qi LS, Huang B. Chen B, et al. Among authors: qi ls. Cell. 2013 Dec 19;155(7):1479-91. doi: 10.1016/j.cell.2013.12.001. Cell. 2013. PMID: 24360272 Free PMC article.

5

Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.

Zalatan JG, Lee ME, Almeida R, Gilbert LA, Whitehead EH, La Russa M, Tsai JC, Weissman JS, Dueber JE, Qi LS, Lim WA. Zalatan JG, et al. Among authors: qi ls. Cell. 2015 Jan 15;160(1-2):339-50. doi: 10.1016/j.cell.2014.11.052. Epub 2014 Dec 18. Cell. 2015. PMID: 25533786 Free PMC article.

6

Small molecules enhance CRISPR genome editing in pluripotent stem cells.

Yu C, Liu Y, Ma T, Liu K, Xu S, Zhang Y, Liu H, La Russa M, Xie M, Ding S, Qi LS. Yu C, et al. Among authors: qi ls. Cell Stem Cell. 2015 Feb 5;16(2):142-7. doi: 10.1016/j.stem.2015.01.003. Cell Stem Cell. 2015. PMID: 25658371 Free PMC article.

7

Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation.

Dominguez AA, Lim WA, Qi LS. Dominguez AA, et al. Among authors: qi ls. Nat Rev Mol Cell Biol. 2016 Jan;17(1):5-15. doi: 10.1038/nrm.2015.2. Epub 2015 Dec 16. Nat Rev Mol Cell Biol. 2016. PMID: 26670017 Free PMC article. Review.

8

CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.

Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, Gilbert LA, Krogan NJ, Sheikh SP, Weissman JS, Qi LS, So PL, Conklin BR. Mandegar MA, et al. Among authors: qi ls. Cell Stem Cell. 2016 Apr 7;18(4):541-53. doi: 10.1016/j.stem.2016.01.022. Epub 2016 Mar 10. Cell Stem Cell. 2016. PMID: 26971820 Free PMC article.

9

A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria.

Peters JM, Colavin A, Shi H, Czarny TL, Larson MH, Wong S, Hawkins JS, Lu CHS, Koo BM, Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, Huang KC, Gross CA. Peters JM, et al. Among authors: qi ls. Cell. 2016 Jun 2;165(6):1493-1506. doi: 10.1016/j.cell.2016.05.003. Epub 2016 May 26. Cell. 2016. PMID: 27238023 Free PMC article.

10

Applications of CRISPR Genome Engineering in Cell Biology.

Wang F, Qi LS. Wang F, et al. Among authors: qi ls. Trends Cell Biol. 2016 Nov;26(11):875-888. doi: 10.1016/j.tcb.2016.08.004. Epub 2016 Sep 3. Trends Cell Biol. 2016. PMID: 27599850 Free PMC article. Review.

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