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Chalcogenium-AZT Derivatives: A Plausible Strategy To Tackle The RT-Inhibitors-Related Oxidative Stress While Maintaining Their Anti- HIV Properties.
Sarturi JM, Dornelles L, Segatto NV, Collares T, Seixas FK, Piccoli BC, da Silva FD, Omage FB, da Rocha JBT, Balaguez RA, Alves D, Lenardão EJ, Lopes EF, Kula-Pacurar A, Pyrc K, Sancineto L, Rodrigues OED. Sarturi JM, et al. Among authors: pyrc k. Curr Med Chem. 2023;30(21):2449-2462. doi: 10.2174/0929867329666220906095438. Curr Med Chem. 2023. PMID: 36065927
Inhibition of Herpes Simplex Viruses by Cationic Dextran Derivatives.
Pachota M, Klysik K, Synowiec A, Ciejka J, Szczubiałka K, Pyrć K, Nowakowska M. Pachota M, et al. Among authors: pyrc k. J Med Chem. 2017 Oct 26;60(20):8620-8630. doi: 10.1021/acs.jmedchem.7b01189. Epub 2017 Oct 6. J Med Chem. 2017. PMID: 28956914
Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of Mpro and Its Antiviral Activity in Cells against SARS-CoV-2.
Mangiavacchi F, Botwina P, Menichetti E, Bagnoli L, Rosati O, Marini F, Fonseca SF, Abenante L, Alves D, Dabrowska A, Kula-Pacurar A, Ortega-Alarcon D, Jimenez-Alesanco A, Ceballos-Laita L, Vega S, Rizzuti B, Abian O, Lenardão EJ, Velazquez-Campoy A, Pyrc K, Sancineto L, Santi C. Mangiavacchi F, et al. Among authors: pyrc k. Int J Mol Sci. 2021 Jun 30;22(13):7048. doi: 10.3390/ijms22137048. Int J Mol Sci. 2021. PMID: 34208928 Free PMC article.
l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells.
Sancineto L, Ostacolo C, Ortega-Alarcon D, Jimenez-Alesanco A, Ceballos-Laita L, Vega S, Abian O, Velazquez-Campoy A, Moretti S, Dabrowska A, Botwina P, Synowiec A, Kula-Pacurar A, Pyrc K, Iraci N, Santi C. Sancineto L, et al. Among authors: pyrc k. Molecules. 2021 Oct 7;26(19):6062. doi: 10.3390/molecules26196062. Molecules. 2021. PMID: 34641606 Free PMC article.
Ceragenins exhibit antiviral activity against SARS-CoV-2 by increasing the expression and release of type I interferons upon activation of the host's immune response.
Suprewicz Ł, Szczepański A, Lenart M, Piktel E, Fiedoruk K, Barreto-Duran E, Kula-Pacurar A, Savage PB, Milewska A, Bucki R, Pyrć K. Suprewicz Ł, et al. Among authors: pyrc k. Antiviral Res. 2023 Sep;217:105676. doi: 10.1016/j.antiviral.2023.105676. Epub 2023 Jul 20. Antiviral Res. 2023. PMID: 37481038
Phosphonate inhibitors of West Nile virus NS2B/NS3 protease.
Skoreński M, Milewska A, Pyrć K, Sieńczyk M, Oleksyszyn J. Skoreński M, et al. Among authors: pyrc k. J Enzyme Inhib Med Chem. 2019 Dec;34(1):8-14. doi: 10.1080/14756366.2018.1506772. J Enzyme Inhib Med Chem. 2019. PMID: 30362835 Free PMC article.
130 results