Pynnönen H - Search Results

1

Targeting CD33+ acute myeloid leukemia with GLK-33, a lintuzumab-auristatin conjugate with a wide therapeutic window.

Satomaa T, Pynnönen H, Aitio O, Hiltunen JO, Pitkänen V, Lähteenmäki T, Kotiranta T, Heiskanen A, Hänninen AL, Niemelä R, Helin J, Kuusanmaki H, Vänttinen I, Rathod R, Nieminen AI, Yatkin E, Heckman CA, Kontro M, Saarinen J. Satomaa T, et al. Among authors: pynnonen h. Mol Cancer Ther. 2024 Apr 2. doi: 10.1158/1535-7163.MCT-23-0720. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38561023

2

Trastuzumab-MMAU Antibody-Auristatin Conjugates: Valine-Glucoserine Linker with Stabilized Maleimide Conjugation Improves In Vivo Efficacy and Tolerability.

Goldberg SD, Satomaa T, Aina O, Aitio O, Burke K, Dudkin V, Geist B, Irrechukwu O, Hänninen AL, Heiskanen A, Helin J, Hiltunen JO, Kinyamu-Akunda J, Klein DM, Kohli N, Kotiranta T, Lähteenmäki T, Niemelä R, Pitkänen V, Pynnönen H, Rittase W, Wiley K, Zhou J, Saarinen J. Goldberg SD, et al. Among authors: pynnonen h. Mol Cancer Ther. 2024 Feb 7. doi: 10.1158/1535-7163.MCT-23-0591. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38324296

3

Hydrophilic Auristatin Glycoside Payload Enables Improved Antibody-Drug Conjugate Efficacy and Biocompatibility.

Satomaa T, Pynnönen H, Vilkman A, Kotiranta T, Pitkänen V, Heiskanen A, Herpers B, Price LS, Helin J, Saarinen J. Satomaa T, et al. Among authors: pynnonen h. Antibodies (Basel). 2018 Mar 22;7(2):15. doi: 10.3390/antib7020015. Antibodies (Basel). 2018. PMID: 31544867 Free PMC article.

4

Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody-Drug Conjugation Chemistry.

Ekholm FS, Pynnönen H, Vilkman A, Pitkänen V, Helin J, Saarinen J, Satomaa T. Ekholm FS, et al. Among authors: pynnonen h. ChemMedChem. 2016 Nov 21;11(22):2501-2505. doi: 10.1002/cmdc.201600372. Epub 2016 Oct 27. ChemMedChem. 2016. PMID: 27786414

5

Synthesis of the copper chelator TGTA and evaluation of its ability to protect biomolecules from copper induced degradation during copper catalyzed azide-alkyne bioconjugation reactions.

Ekholm FS, Pynnönen H, Vilkman A, Koponen J, Helin J, Satomaa T. Ekholm FS, et al. Among authors: pynnonen h. Org Biomol Chem. 2016 Jan 21;14(3):849-52. doi: 10.1039/c5ob02133b. Epub 2015 Dec 8. Org Biomol Chem. 2016. PMID: 26647226

6

Quantitation of 4-O-methylglucuronic acid from plant cell walls.

Chong SL, Koutaniemi S, Virkki L, Pynnönen H, Tuomainen P, Tenkanen M. Chong SL, et al. Among authors: pynnonen h. Carbohydr Polym. 2013 Jan 16;91(2):626-30. doi: 10.1016/j.carbpol.2012.08.078. Epub 2012 Aug 30. Carbohydr Polym. 2013. PMID: 23121956

7

Superhydrophobic and superoleophobic nanocellulose aerogel membranes as bioinspired cargo carriers on water and oil.

Jin H, Kettunen M, Laiho A, Pynnönen H, Paltakari J, Marmur A, Ikkala O, Ras RH. Jin H, et al. Among authors: pynnonen h. Langmuir. 2011 Mar 1;27(5):1930-4. doi: 10.1021/la103877r. Epub 2011 Jan 19. Langmuir. 2011. PMID: 21247181

8

Structural analysis of enzyme-resistant isomaltooligosaccharides reveals the elongation of α-(1→3)-linked branches in Weissella confusa dextran.

Maina NH, Virkki L, Pynnönen H, Maaheimo H, Tenkanen M. Maina NH, et al. Among authors: pynnonen h. Biomacromolecules. 2011 Feb 14;12(2):409-18. doi: 10.1021/bm1011536. Epub 2011 Jan 5. Biomacromolecules. 2011. PMID: 21207960

9

[Practical education for nursing and current efforts for improving care in the Helsinki University Hospital's Maternity Clinic].

Pynnönen H. Pynnönen H. Katilolehti. 1993 May;98(3):7-8. Katilolehti. 1993. PMID: 8230949 Finnish. No abstract available.

10

[Educational reform at the intermediate level and the midwife as a woman's nurse].

Pynnönen H. Pynnönen H. Katilolehti. 1986 Sep;91(6):246-8. Katilolehti. 1986. PMID: 3642055 Finnish. No abstract available.

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