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HIV-1 adaptation to antigen processing results in population-level immune evasion and affects subtype diversification.
Tenzer S, Crawford H, Pymm P, Gifford R, Sreenu VB, Weimershaus M, de Oliveira T, Burgevin A, Gerstoft J, Akkad N, Lunn D, Fugger L, Bell J, Schild H, van Endert P, Iversen AKN. Tenzer S, et al. Among authors: pymm p. Cell Rep. 2014 Apr 24;7(2):448-463. doi: 10.1016/j.celrep.2014.03.031. Epub 2014 Apr 13. Cell Rep. 2014. PMID: 24726370 Free PMC article.
Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.
O'Connor GM, Vivian JP, Gostick E, Pymm P, Lafont BA, Price DA, Rossjohn J, Brooks AG, McVicar DW. O'Connor GM, et al. Among authors: pymm p. J Virol. 2015 May;89(10):5213-21. doi: 10.1128/JVI.03586-14. Epub 2015 Mar 4. J Virol. 2015. PMID: 25740999 Free PMC article.
Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition.
Saunders PM, Pymm P, Pietra G, Hughes VA, Hitchen C, O'Connor GM, Loiacono F, Widjaja J, Price DA, Falco M, Mingari MC, Moretta L, McVicar DW, Rossjohn J, Brooks AG, Vivian JP. Saunders PM, et al. Among authors: pymm p. J Exp Med. 2016 May 2;213(5):791-807. doi: 10.1084/jem.20152023. Epub 2016 Apr 4. J Exp Med. 2016. PMID: 27045007 Free PMC article.
MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Pymm P, Illing PT, Ramarathinam SH, O'Connor GM, Hughes VA, Hitchen C, Price DA, Ho BK, McVicar DW, Brooks AG, Purcell AW, Rossjohn J, Vivian JP. Pymm P, et al. Nat Struct Mol Biol. 2017 Apr;24(4):387-394. doi: 10.1038/nsmb.3381. Epub 2017 Feb 20. Nat Struct Mol Biol. 2017. PMID: 28218747 Free PMC article.
Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.
Martin MP, Naranbhai V, Shea PR, Qi Y, Ramsuran V, Vince N, Gao X, Thomas R, Brumme ZL, Carlson JM, Wolinsky SM, Goedert JJ, Walker BD, Segal FP, Deeks SG, Haas DW, Migueles SA, Connors M, Michael N, Fellay J, Gostick E, Llewellyn-Lacey S, Price DA, Lafont BA, Pymm P, Saunders PM, Widjaja J, Wong SC, Vivian JP, Rossjohn J, Brooks AG, Carrington M. Martin MP, et al. Among authors: pymm p. J Clin Invest. 2018 May 1;128(5):1903-1912. doi: 10.1172/JCI98463. Epub 2018 Apr 3. J Clin Invest. 2018. PMID: 29461980 Free PMC article. Clinical Trial.
Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Wheatley AK, Pymm P, Esterbauer R, Dietrich MH, Lee WS, Drew D, Kelly HG, Chan LJ, Mordant FL, Black KA, Adair A, Tan HX, Juno JA, Wragg KM, Amarasena T, Lopez E, Selva KJ, Haycroft ER, Cooney JP, Venugopal H, Tan LL, O Neill MT, Allison CC, Cromer D, Davenport MP, Bowen RA, Chung AW, Pellegrini M, Liddament MT, Glukhova A, Subbarao K, Kent SJ, Tham WH. Wheatley AK, et al. Among authors: pymm p. Cell Rep. 2021 Oct 12;37(2):109822. doi: 10.1016/j.celrep.2021.109822. Epub 2021 Sep 25. Cell Rep. 2021. PMID: 34610292 Free PMC article.
28 results