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Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically.
Putoczki TL, Thiem S, Loving A, Busuttil RA, Wilson NJ, Ziegler PK, Nguyen PM, Preaudet A, Farid R, Edwards KM, Boglev Y, Luwor RB, Jarnicki A, Horst D, Boussioutas A, Heath JK, Sieber OM, Pleines I, Kile BT, Nash A, Greten FR, McKenzie BS, Ernst M. Putoczki TL, et al. Cancer Cell. 2013 Aug 12;24(2):257-71. doi: 10.1016/j.ccr.2013.06.017. Cancer Cell. 2013. PMID: 23948300 Free article.
The Interleukin-11/IL-11 Receptor Promotes Glioblastoma Survival and Invasion under Glucose-Starved Conditions through Enhanced Glutaminolysis.
Stuart SF, Bezawork-Geleta A, Areeb Z, Gomez J, Tsui V, Zulkifli A, Paradiso L, Jones J, Nguyen HPT, Putoczki TL, Licciardi PV, Kannourakis G, Morokoff AP, Achuthan AA, Luwor RB. Stuart SF, et al. Among authors: putoczki tl. Int J Mol Sci. 2023 Feb 8;24(4):3356. doi: 10.3390/ijms24043356. Int J Mol Sci. 2023. PMID: 36834778 Free PMC article.
Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice.
Poh AR, Dwyer AR, Eissmann MF, Chand AL, Baloyan D, Boon L, Murrey MW, Whitehead L, O'Brien M, Lowell CA, Putoczki TL, Pixley FJ, O'Donoghue RJJ, Ernst M. Poh AR, et al. Among authors: putoczki tl. Cancer Immunol Res. 2020 Apr;8(4):428-435. doi: 10.1158/2326-6066.CIR-19-0623. Epub 2020 Jan 28. Cancer Immunol Res. 2020. PMID: 31992566 Free PMC article.
85 results