Punganuru SR - Search Results

1

Posttranslational Regulation of O(6)-Methylguanine-DNA Methyltransferase (MGMT) and New Opportunities for Treatment of Brain Cancers.

Srivenugopal KS, Rawat A, Niture SK, Paranjpe A, Velu C, Venugopal SN, Madala HR, Basak D, Punganuru SR. Srivenugopal KS, et al. Among authors: punganuru sr. Mini Rev Med Chem. 2016;16(6):455-64. doi: 10.2174/1389557515666150722101046. Mini Rev Med Chem. 2016. PMID: 26202203 Review.

2

Design and synthesis of a C7-aryl piperlongumine derivative with potent antimicrotubule and mutant p53-reactivating properties.

Punganuru SR, Madala HR, Venugopal SN, Samala R, Mikelis C, Srivenugopal KS. Punganuru SR, et al. Eur J Med Chem. 2016 Jan 1;107:233-44. doi: 10.1016/j.ejmech.2015.10.052. Epub 2015 Nov 2. Eur J Med Chem. 2016. PMID: 26599530

3

New insights into estrogenic regulation of O⁶-methylguanine DNA-methyltransferase (MGMT) in human breast cancer cells: Co-degradation of ER-α and MGMT proteins by fulvestrant or O⁶-benzylguanine indicates fresh avenues for therapy.

Paranjpe A, Bailey NI, Konduri S, Bobustuc GC, Ali-Osman F, Yusuf MA, Punganuru SR, Madala HR, Basak D, Mostofa A, Srivenugopal KS. Paranjpe A, et al. Among authors: punganuru sr. J Biomed Res. 2016 Sep;30(5):393-410. doi: 10.7555/JBR.30.20160040. Epub 2016 Jun 10. J Biomed Res. 2016. PMID: 27845303 Free PMC article.

4

S-phase Specific Downregulation of Human O⁶-Methylguanine DNA Methyltransferase (MGMT) and its Serendipitous Interactions with PCNA and p21^cip1 Proteins in Glioma Cells.

Mostofa A, Punganuru SR, Madala HR, Srivenugopal KS. Mostofa A, et al. Among authors: punganuru sr. Neoplasia. 2018 Apr;20(4):305-323. doi: 10.1016/j.neo.2018.01.010. Epub 2018 Mar 3. Neoplasia. 2018. PMID: 29510343 Free PMC article.

5

Piperlongumine exerts cytotoxic effects against cancer cells with mutant p53 proteins at least in part by restoring the biological functions of the tumor suppressor.

Basak D, Punganuru SR, Srivenugopal KS. Basak D, et al. Among authors: punganuru sr. Int J Oncol. 2016 Apr;48(4):1426-36. doi: 10.3892/ijo.2016.3372. Epub 2016 Feb 3. Int J Oncol. 2016. PMID: 26848023

6

Potent anti-proliferative actions of a non-diuretic glucosamine derivative of ethacrynic acid.

Punganuru SR, Mostofa AGM, Madala HR, Basak D, Srivenugopal KS. Punganuru SR, et al. Bioorg Med Chem Lett. 2016 Jun 15;26(12):2829-2833. doi: 10.1016/j.bmcl.2016.04.062. Epub 2016 Apr 22. Bioorg Med Chem Lett. 2016. PMID: 27156773

7

The Process and Regulatory Components of Inflammation in Brain Oncogenesis.

Mostofa AG, Punganuru SR, Madala HR, Al-Obaide M, Srivenugopal KS. Mostofa AG, et al. Among authors: punganuru sr. Biomolecules. 2017 Mar 27;7(2):34. doi: 10.3390/biom7020034. Biomolecules. 2017. PMID: 28346397 Free PMC article. Review.

8

Brain- and brain tumor-penetrating disulfiram nanoparticles: Sequence of cytotoxic events and efficacy in human glioma cell lines and intracranial xenografts.

Madala HR, Punganuru SR, Ali-Osman F, Zhang R, Srivenugopal KS. Madala HR, et al. Among authors: punganuru sr. Oncotarget. 2017 Dec 15;9(3):3459-3482. doi: 10.18632/oncotarget.23320. eCollection 2018 Jan 9. Oncotarget. 2017. PMID: 29423059 Free PMC article.

9

Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies.

Madala HR, Punganuru SR, Arutla V, Misra S, Thomas TJ, Srivenugopal KS. Madala HR, et al. Among authors: punganuru sr. Cancers (Basel). 2018 Feb 11;10(2):49. doi: 10.3390/cancers10020049. Cancers (Basel). 2018. PMID: 29439493 Free PMC article. Review.

10

Selective killing of human breast cancer cells by the styryl lactone (R)-goniothalamin is mediated by glutathione conjugation, induction of oxidative stress and marked reactivation of the R175H mutant p53 protein.

Punganuru SR, Madala HR, Arutla V, Srivenugopal KS. Punganuru SR, et al. Carcinogenesis. 2018 Dec 13;39(11):1399-1410. doi: 10.1093/carcin/bgy093. Carcinogenesis. 2018. PMID: 30010803

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