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Gluten Degradation, Pharmacokinetics, Safety, and Tolerability of TAK-062, an Engineered Enzyme to Treat Celiac Disease.
Gastroenterology. 2021 Jul;161(1):81-93.e3. doi: 10.1053/j.gastro.2021.03.019. Epub 2021 Mar 17.
Gastroenterology. 2021.
PMID: 33741317
Free article.
Clinical Trial.
Engineering of Kuma030: A Gliadin Peptidase That Rapidly Degrades Immunogenic Gliadin Peptides in Gastric Conditions.
Wolf C, Siegel JB, Tinberg C, Camarca A, Gianfrani C, Paski S, Guan R, Montelione G, Baker D, Pultz IS.
Wolf C, et al. Among authors: pultz is.
J Am Chem Soc. 2015 Oct 14;137(40):13106-13. doi: 10.1021/jacs.5b08325. Epub 2015 Sep 29.
J Am Chem Soc. 2015.
PMID: 26374198
Free PMC article.
Item in Clipboard
Computational design of an α-gliadin peptidase.
Gordon SR, Stanley EJ, Wolf S, Toland A, Wu SJ, Hadidi D, Mills JH, Baker D, Pultz IS, Siegel JB.
Gordon SR, et al. Among authors: pultz is.
J Am Chem Soc. 2012 Dec 19;134(50):20513-20. doi: 10.1021/ja3094795. Epub 2012 Dec 5.
J Am Chem Soc. 2012.
PMID: 23153249
Free PMC article.
Item in Clipboard
Expanding the product profile of a microbial alkane biosynthetic pathway.
Harger M, Zheng L, Moon A, Ager C, An JH, Choe C, Lai YL, Mo B, Zong D, Smith MD, Egbert RG, Mills JH, Baker D, Pultz IS, Siegel JB.
Harger M, et al. Among authors: pultz is.
ACS Synth Biol. 2013 Jan 18;2(1):59-62. doi: 10.1021/sb300061x. Epub 2012 Sep 26.
ACS Synth Biol. 2013.
PMID: 23656326
Free PMC article.
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The response threshold of Salmonella PilZ domain proteins is determined by their binding affinities for c-di-GMP.
Pultz IS, Christen M, Kulasekara HD, Kennard A, Kulasekara B, Miller SI.
Pultz IS, et al.
Mol Microbiol. 2012 Dec;86(6):1424-40. doi: 10.1111/mmi.12066. Epub 2012 Nov 19.
Mol Microbiol. 2012.
PMID: 23163901
Free PMC article.
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The bacterial second messenger c-di-GMP: mechanisms of signalling.
Mills E, Pultz IS, Kulasekara HD, Miller SI.
Mills E, et al. Among authors: pultz is.
Cell Microbiol. 2011 Aug;13(8):1122-9. doi: 10.1111/j.1462-5822.2011.01619.x. Epub 2011 Jun 24.
Cell Microbiol. 2011.
PMID: 21707905
Review.
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Nucleolar trafficking of the mouse mammary tumor virus gag protein induced by interaction with ribosomal protein L9.
Beyer AR, Bann DV, Rice B, Pultz IS, Kane M, Goff SP, Golovkina TV, Parent LJ.
Beyer AR, et al. Among authors: pultz is.
J Virol. 2013 Jan;87(2):1069-82. doi: 10.1128/JVI.02463-12. Epub 2012 Nov 7.
J Virol. 2013.
PMID: 23135726
Free PMC article.
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