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Characterization of a Novel ACE2-Based Therapeutic with Enhanced Rather than Reduced Activity against SARS-CoV-2 Variants.
Ferrari M, Mekkaoui L, Ilca FT, Akbar Z, Bughda R, Lamb K, Ward K, Parekh F, Karattil R, Allen C, Wu P, Baldan V, Mattiuzzo G, Bentley EM, Takeuchi Y, Sillibourne J, Datta P, Kinna A, Pule M, Onuoha SC. Ferrari M, et al. Among authors: pule m. J Virol. 2021 Sep 9;95(19):e0068521. doi: 10.1128/JVI.00685-21. Epub 2021 Sep 9. J Virol. 2021. PMID: 34287040 Free PMC article.
An APRIL-based chimeric antigen receptor for dual targeting of BCMA and TACI in multiple myeloma.
Lee L, Draper B, Chaplin N, Philip B, Chin M, Galas-Filipowicz D, Onuoha S, Thomas S, Baldan V, Bughda R, Maciocia P, Kokalaki E, Neves MP, Patel D, Rodriguez-Justo M, Francis J, Yong K, Pule M. Lee L, et al. Among authors: pule m. Blood. 2018 Feb 15;131(7):746-758. doi: 10.1182/blood-2017-05-781351. Epub 2017 Dec 28. Blood. 2018. PMID: 29284597 Free PMC article.
A Rapamycin-Activated Caspase 9-Based Suicide Gene.
Stavrou M, Philip B, Traynor-White C, Davis CG, Onuoha S, Cordoba S, Thomas S, Pule M. Stavrou M, et al. Among authors: pule m. Mol Ther. 2018 May 2;26(5):1266-1276. doi: 10.1016/j.ymthe.2018.03.001. Epub 2018 Mar 9. Mol Ther. 2018. PMID: 29661681 Free PMC article.
Lentiviral Vector Purification Using Genetically Encoded Biotin Mimic in Packaging Cell.
Mekkaoui L, Parekh F, Kotsopoulou E, Darling D, Dickson G, Cheung GW, Chan L, MacLellan-Gibson K, Mattiuzzo G, Farzaneh F, Takeuchi Y, Pule M. Mekkaoui L, et al. Among authors: pule m. Mol Ther Methods Clin Dev. 2018 Oct 23;11:155-165. doi: 10.1016/j.omtm.2018.10.008. eCollection 2018 Dec 14. Mol Ther Methods Clin Dev. 2018. PMID: 30547049 Free PMC article.
Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR.
Ghorashian S, Kramer AM, Onuoha S, Wright G, Bartram J, Richardson R, Albon SJ, Casanovas-Company J, Castro F, Popova B, Villanueva K, Yeung J, Vetharoy W, Guvenel A, Wawrzyniecka PA, Mekkaoui L, Cheung GW, Pinner D, Chu J, Lucchini G, Silva J, Ciocarlie O, Lazareva A, Inglott S, Gilmour KC, Ahsan G, Ferrari M, Manzoor S, Champion K, Brooks T, Lopes A, Hackshaw A, Farzaneh F, Chiesa R, Rao K, Bonney D, Samarasinghe S, Goulden N, Vora A, Veys P, Hough R, Wynn R, Pule MA, Amrolia PJ. Ghorashian S, et al. Among authors: pule ma. Nat Med. 2019 Sep;25(9):1408-1414. doi: 10.1038/s41591-019-0549-5. Epub 2019 Sep 2. Nat Med. 2019. PMID: 31477906 Clinical Trial.
120 results