Puglielli L - Search Results

1

Alzheimer's disease: the cholesterol connection.

Puglielli L, Tanzi RE, Kovacs DM. Puglielli L, et al. Nat Neurosci. 2003 Apr;6(4):345-51. doi: 10.1038/nn0403-345. Nat Neurosci. 2003. PMID: 12658281 Review.

2

Role of acyl-coenzyme a: cholesterol acyltransferase activity in the processing of the amyloid precursor protein.

Puglielli L, Ellis BC, Ingano LA, Kovacs DM. Puglielli L, et al. J Mol Neurosci. 2004;24(1):93-6. doi: 10.1385/JMN:24:1:093. J Mol Neurosci. 2004. PMID: 15314256 Review.

3

Alzheimer disease beta-amyloid activity mimics cholesterol oxidase.

Puglielli L, Friedlich AL, Setchell KD, Nagano S, Opazo C, Cherny RA, Barnham KJ, Wade JD, Melov S, Kovacs DM, Bush AI. Puglielli L, et al. J Clin Invest. 2005 Sep;115(9):2556-63. doi: 10.1172/JCI23610. Epub 2005 Aug 25. J Clin Invest. 2005. PMID: 16127459 Free PMC article.

4

Novel N-terminal cleavage of APP precludes Abeta generation in ACAT-defective AC29 cells.

Huttunen HJ, Puglielli L, Ellis BC, MacKenzie Ingano LA, Kovacs DM. Huttunen HJ, et al. Among authors: puglielli l. J Mol Neurosci. 2009 Jan;37(1):6-15. doi: 10.1007/s12031-008-9088-0. Epub 2008 Jul 10. J Mol Neurosci. 2009. PMID: 18618086 Free PMC article.

5

Alzheimer disease: 100 years later.

Puglielli L, Kovacs DM. Puglielli L, et al. Rev Med Chil. 2001 May;129(5):569-75. doi: 10.4067/s0034-98872001000500015. Rev Med Chil. 2001. PMID: 11464541 Review.

6

Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide.

Puglielli L, Konopka G, Pack-Chung E, Ingano LA, Berezovska O, Hyman BT, Chang TY, Tanzi RE, Kovacs DM. Puglielli L, et al. Nat Cell Biol. 2001 Oct;3(10):905-12. doi: 10.1038/ncb1001-905. Nat Cell Biol. 2001. PMID: 11584272

7

Ceramide stabilizes beta-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid beta-peptide biogenesis.

Puglielli L, Ellis BC, Saunders AJ, Kovacs DM. Puglielli L, et al. J Biol Chem. 2003 May 30;278(22):19777-83. doi: 10.1074/jbc.M300466200. Epub 2003 Mar 20. J Biol Chem. 2003. PMID: 12649271 Free article. Retracted.

8

The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease.

Hutter-Paier B, Huttunen HJ, Puglielli L, Eckman CB, Kim DY, Hofmeister A, Moir RD, Domnitz SB, Frosch MP, Windisch M, Kovacs DM. Hutter-Paier B, et al. Among authors: puglielli l. Neuron. 2004 Oct 14;44(2):227-38. doi: 10.1016/j.neuron.2004.08.043. Neuron. 2004. PMID: 15473963 Free article.

9

Withdrawal: Ceramide stabilizes β-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid β-peptide biogenesis.

Puglielli L, Ellis BC, Saunders AJ, Kovacs DM. Puglielli L, et al. J Biol Chem. 2022 Jun;298(6):102052. doi: 10.1016/j.jbc.2022.102052. Epub 2022 May 26. J Biol Chem. 2022. PMID: 35635926 Free PMC article. No abstract available.

10

Cerebrospinal fluid sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer's disease.

Mielke MM, Haughey NJ, Bandaru VVR, Zetterberg H, Blennow K, Andreasson U, Johnson SC, Gleason CE, Blazel HM, Puglielli L, Sager MA, Asthana S, Carlsson CM. Mielke MM, et al. Among authors: puglielli l. Neurobiol Aging. 2014 Nov;35(11):2486-2494. doi: 10.1016/j.neurobiolaging.2014.05.019. Epub 2014 May 27. Neurobiol Aging. 2014. PMID: 24952994 Free PMC article.

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