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NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer.
Loskutov YV, Kozyulina PY, Kozyreva VK, Ice RJ, Jones BC, Roston TJ, Smolkin MB, Ivanov AV, Wysolmerski RB, Pugacheva EN. Loskutov YV, et al. Among authors: pugacheva en. Oncogene. 2015 Jul;34(28):3662-75. doi: 10.1038/onc.2014.297. Epub 2014 Sep 22. Oncogene. 2015. PMID: 25241893 Free PMC article.
NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis.
McLaughlin SL, Ice RJ, Rajulapati A, Kozyulina PY, Livengood RH, Kozyreva VK, Loskutov YV, Culp MV, Weed SA, Ivanov AV, Pugacheva EN. McLaughlin SL, et al. Among authors: pugacheva en. Mol Cancer Res. 2014 Jan;12(1):69-81. doi: 10.1158/1541-7786.MCR-13-0300. Epub 2013 Nov 7. Mol Cancer Res. 2014. PMID: 24202705 Free PMC article.
Combination of Eribulin and Aurora A Inhibitor MLN8237 Prevents Metastatic Colonization and Induces Cytotoxic Autophagy in Breast Cancer.
Kozyreva VK, Kiseleva AA, Ice RJ, Jones BC, Loskutov YV, Matalkah F, Smolkin MB, Marinak K, Livengood RH, Salkeni MA, Wen S, Hazard HW, Layne GP, Walsh CM, Cantrell PS, Kilby GW, Mahavadi S, Shah N, Pugacheva EN. Kozyreva VK, et al. Among authors: pugacheva en. Mol Cancer Ther. 2016 Aug;15(8):1809-22. doi: 10.1158/1535-7163.MCT-15-0688. Epub 2016 May 27. Mol Cancer Ther. 2016. PMID: 27235164 Free PMC article.
KAP1 promotes proliferation and metastatic progression of breast cancer cells.
Addison JB, Koontz C, Fugett JH, Creighton CJ, Chen D, Farrugia MK, Padon RR, Voronkova MA, McLaughlin SL, Livengood RH, Lin CC, Ruppert JM, Pugacheva EN, Ivanov AV. Addison JB, et al. Among authors: pugacheva en. Cancer Res. 2015 Jan 15;75(2):344-55. doi: 10.1158/0008-5472.CAN-14-1561. Epub 2014 Nov 24. Cancer Res. 2015. PMID: 25421577 Free PMC article.
54 results