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Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy.
Aypek H, Krisp C, Lu S, Liu S, Kylies D, Kretz O, Wu G, Moritz M, Amann K, Benz K, Tong P, Hu ZM, Alsulaiman SM, Khan AO, Grohmann M, Wagner T, Müller-Deile J, Schlüter H, Puelles VG, Bergmann C, Huber TB, Grahammer F. Aypek H, et al. Among authors: puelles vg. J Clin Invest. 2022 May 2;132(9):e147253. doi: 10.1172/JCI147253. J Clin Invest. 2022. PMID: 35499085 Free PMC article.
DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation.
Wanner N, Vornweg J, Combes A, Wilson S, Plappert J, Rafflenbeul G, Puelles VG, Rahman RU, Liwinski T, Lindner S, Grahammer F, Kretz O, Wlodek ME, Romano T, Moritz KM, Boerries M, Busch H, Bonn S, Little MH, Bechtel-Walz W, Huber TB. Wanner N, et al. Among authors: puelles vg. J Am Soc Nephrol. 2019 Jan;30(1):63-78. doi: 10.1681/ASN.2018070736. Epub 2018 Dec 5. J Am Soc Nephrol. 2019. PMID: 30518531 Free PMC article.
Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics.
Brinkkoetter PT, Bork T, Salou S, Liang W, Mizi A, Özel C, Koehler S, Hagmann HH, Ising C, Kuczkowski A, Schnyder S, Abed A, Schermer B, Benzing T, Kretz O, Puelles VG, Lagies S, Schlimpert M, Kammerer B, Handschin C, Schell C, Huber TB. Brinkkoetter PT, et al. Among authors: puelles vg. Cell Rep. 2019 Apr 30;27(5):1551-1566.e5. doi: 10.1016/j.celrep.2019.04.012. Cell Rep. 2019. PMID: 31042480 Free PMC article.
The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression.
Lazareth H, Henique C, Lenoir O, Puelles VG, Flamant M, Bollée G, Fligny C, Camus M, Guyonnet L, Millien C, Gaillard F, Chipont A, Robin B, Fabrega S, Dhaun N, Camerer E, Kretz O, Grahammer F, Braun F, Huber TB, Nochy D, Mandet C, Bruneval P, Mesnard L, Thervet E, Karras A, Le Naour F, Rubinstein E, Boucheix C, Alexandrou A, Moeller MJ, Bouzigues C, Tharaux PL. Lazareth H, et al. Among authors: puelles vg. Nat Commun. 2019 Jul 24;10(1):3303. doi: 10.1038/s41467-019-11013-2. Nat Commun. 2019. PMID: 31341160 Free PMC article.
mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans.
Puelles VG, van der Wolde JW, Wanner N, Scheppach MW, Cullen-McEwen LA, Bork T, Lindenmeyer MT, Gernhold L, Wong MN, Braun F, Cohen CD, Kett MM, Kuppe C, Kramann R, Saritas T, van Roeyen CR, Moeller MJ, Tribolet L, Rebello R, Sun YB, Li J, Müller-Newen G, Hughson MD, Hoy WE, Person F, Wiech T, Ricardo SD, Kerr PG, Denton KM, Furic L, Huber TB, Nikolic-Paterson DJ, Bertram JF. Puelles VG, et al. JCI Insight. 2019 Sep 19;4(18):e99271. doi: 10.1172/jci.insight.99271. JCI Insight. 2019. PMID: 31534053 Free PMC article.
Multiorgan and Renal Tropism of SARS-CoV-2.
Puelles VG, Lütgehetmann M, Lindenmeyer MT, Sperhake JP, Wong MN, Allweiss L, Chilla S, Heinemann A, Wanner N, Liu S, Braun F, Lu S, Pfefferle S, Schröder AS, Edler C, Gross O, Glatzel M, Wichmann D, Wiech T, Kluge S, Pueschel K, Aepfelbacher M, Huber TB. Puelles VG, et al. N Engl J Med. 2020 Aug 6;383(6):590-592. doi: 10.1056/NEJMc2011400. Epub 2020 May 13. N Engl J Med. 2020. PMID: 32402155 Free PMC article. No abstract available.
Interleukin-9 protects from early podocyte injury and progressive glomerulosclerosis in Adriamycin-induced nephropathy.
Xiong T, Attar M, Gnirck AC, Wunderlich M, Becker M, Rickassel C, Puelles VG, Meyer-Schwesinger C, Wiech T, Nies JF, Divivier M, Fuchs T, Schulze Zur Wiesch J, Taipaleenmäki H, Hoxha E, Wirtz S, Huber TB, Panzer U, Turner JE. Xiong T, et al. Among authors: puelles vg. Kidney Int. 2020 Sep;98(3):615-629. doi: 10.1016/j.kint.2020.04.036. Epub 2020 May 21. Kidney Int. 2020. PMID: 32446933
83 results