Ptacek J - Search Results

1

Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer.

Ptacek J, Zhang D, Qiu L, Kruspe S, Motlova L, Kolenko P, Novakova Z, Shubham S, Havlinova B, Baranova P, Chen SJ, Zou X, Giangrande P, Barinka C. Ptacek J, et al. Nucleic Acids Res. 2020 Nov 4;48(19):11130-11145. doi: 10.1093/nar/gkaa494. Nucleic Acids Res. 2020. PMID: 32525981 Free PMC article.

2

Glutamate carboxypeptidase II: an overview of structural studies and their importance for structure-based drug design and deciphering the reaction mechanism of the enzyme.

Pavlícek J, Ptácek J, Barinka C. Pavlícek J, et al. Among authors: ptacek j. Curr Med Chem. 2012;19(9):1300-9. doi: 10.2174/092986712799462667. Curr Med Chem. 2012. PMID: 22304708 Review.

3

Structural characterization of P1'-diversified urea-based inhibitors of glutamate carboxypeptidase II.

Pavlicek J, Ptacek J, Cerny J, Byun Y, Skultetyova L, Pomper MG, Lubkowski J, Barinka C. Pavlicek J, et al. Among authors: ptacek j. Bioorg Med Chem Lett. 2014 May 15;24(10):2340-5. doi: 10.1016/j.bmcl.2014.03.066. Epub 2014 Mar 28. Bioorg Med Chem Lett. 2014. PMID: 24731280 Free PMC article.

4

Structural and biochemical characterization of the folyl-poly-γ-l-glutamate hydrolyzing activity of human glutamate carboxypeptidase II.

Navrátil M, Ptáček J, Šácha P, Starková J, Lubkowski J, Bařinka C, Konvalinka J. Navrátil M, et al. Among authors: ptacek j. FEBS J. 2014 Jul;281(14):3228-42. doi: 10.1111/febs.12857. Epub 2014 Jun 17. FEBS J. 2014. PMID: 24863754 Free PMC article.

5

Carborane-containing urea-based inhibitors of glutamate carboxypeptidase II: Synthesis and structural characterization.

Youn S, Kim KI, Ptacek J, Ok K, Novakova Z, Kim Y, Koo J, Barinka C, Byun Y. Youn S, et al. Among authors: ptacek j. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5232-6. doi: 10.1016/j.bmcl.2015.09.062. Epub 2015 Sep 26. Bioorg Med Chem Lett. 2015. PMID: 26459214

6

Selection and characterization of Anticalins targeting human prostate-specific membrane antigen (PSMA).

Barinka C, Ptacek J, Richter A, Novakova Z, Morath V, Skerra A. Barinka C, et al. Among authors: ptacek j. Protein Eng Des Sel. 2016 Mar;29(3):105-15. doi: 10.1093/protein/gzv065. Epub 2016 Jan 21. Protein Eng Des Sel. 2016. PMID: 26802163

7

Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity.

Novakova Z, Wozniak K, Jancarik A, Rais R, Wu Y, Pavlicek J, Ferraris D, Havlinova B, Ptacek J, Vavra J, Hin N, Rojas C, Majer P, Slusher BS, Tsukamoto T, Barinka C. Novakova Z, et al. Among authors: ptacek j. J Med Chem. 2016 May 26;59(10):4539-50. doi: 10.1021/acs.jmedchem.5b01806. Epub 2016 Apr 25. J Med Chem. 2016. PMID: 27074627

8

The calcium-binding site of human glutamate carboxypeptidase II is critical for dimerization, thermal stability, and enzymatic activity.

Ptacek J, Nedvedova J, Navratil M, Havlinova B, Konvalinka J, Barinka C. Ptacek J, et al. Protein Sci. 2018 Sep;27(9):1575-1584. doi: 10.1002/pro.3460. Protein Sci. 2018. PMID: 30168215 Free PMC article.

9

Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.

Noonepalle S, Shen S, Ptáček J, Tavares MT, Zhang G, Stránský J, Pavlíček J, Ferreira GM, Hadley M, Pelaez G, Bařinka C, Kozikowski AP, Villagra A. Noonepalle S, et al. Among authors: ptacek j. J Med Chem. 2020 Sep 24;63(18):10246-10262. doi: 10.1021/acs.jmedchem.0c00567. Epub 2020 Sep 2. J Med Chem. 2020. PMID: 32815366

10

Determining Potency of Inhibitors Targeting Histone Deacetylase 6 by Quantification of Acetylated Tubulin in Cells.

Mikesova J, Ondrakova M, Jelinkova I, Ptacek J, Novakova Z, Barinka C. Mikesova J, et al. Among authors: ptacek j. Methods Mol Biol. 2023;2589:455-466. doi: 10.1007/978-1-0716-2788-4_29. Methods Mol Biol. 2023. PMID: 36255642

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