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Rational prioritization strategy allows the design of macrolide derivatives that overcome antibiotic resistance.
Proc Natl Acad Sci U S A. 2021 Nov 16;118(46):e2113632118. doi: 10.1073/pnas.2113632118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34750269
Free PMC article.
Chemical biology: biosynthetic interceptors.
Pryk N, Schulz F.
Pryk N, et al.
Nat Chem. 2015 Feb;7(2):102-4. doi: 10.1038/nchem.2168.
Nat Chem. 2015.
PMID: 25615663
No abstract available.
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Identification of crucial bottlenecks in engineered polyketide biosynthesis.
Grote M, Kushnir S, Pryk N, Möller D, Erver J, Ismail-Ali A, Schulz F.
Grote M, et al. Among authors: pryk n.
Org Biomol Chem. 2019 Jul 14;17(26):6374-6385. doi: 10.1039/c9ob00831d. Epub 2019 May 15.
Org Biomol Chem. 2019.
PMID: 31090778
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Biosynthesis-driven structure-activity relationship study of premonensin-derivatives.
Ismail-Ali A, Fansa EK, Pryk N, Yahiaoui S, Kushnir S, Pflieger M, Wittinghofer A, Schulz F.
Ismail-Ali A, et al. Among authors: pryk n.
Org Biomol Chem. 2016 Aug 10;14(32):7671-5. doi: 10.1039/c6ob01201a.
Org Biomol Chem. 2016.
PMID: 27452503
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