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A median fin derived from the lateral plate mesoderm and the origin of paired fins.
Tzung KW, Lalonde RL, Prummel KD, Mahabaleshwar H, Moran HR, Stundl J, Cass AN, Le Y, Lea R, Dorey K, Tomecka MJ, Zhang C, Brombacher EC, White WT, Roehl HH, Tulenko FJ, Winkler C, Currie PD, Amaya E, Davis MC, Bronner ME, Mosimann C, Carney TJ. Tzung KW, et al. Among authors: prummel kd. Nature. 2023 Jun;618(7965):543-549. doi: 10.1038/s41586-023-06100-w. Epub 2023 May 24. Nature. 2023. PMID: 37225983 Free PMC article.
Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma.
Prummel KD, Crowell HL, Nieuwenhuize S, Brombacher EC, Daetwyler S, Soneson C, Kresoja-Rakic J, Kocere A, Ronner M, Ernst A, Labbaf Z, Clouthier DE, Firulli AB, Sánchez-Iranzo H, Naganathan SR, O'Rourke R, Raz E, Mercader N, Burger A, Felley-Bosco E, Huisken J, Robinson MD, Mosimann C. Prummel KD, et al. Nat Commun. 2022 Mar 30;13(1):1677. doi: 10.1038/s41467-022-29311-7. Nat Commun. 2022. PMID: 35354817 Free PMC article.
The lateral plate mesoderm.
Prummel KD, Nieuwenhuize S, Mosimann C. Prummel KD, et al. Development. 2020 Jun 19;147(12):dev175059. doi: 10.1242/dev.175059. Development. 2020. PMID: 32561665 Free PMC article. Review.
A conserved regulatory program initiates lateral plate mesoderm emergence across chordates.
Prummel KD, Hess C, Nieuwenhuize S, Parker HJ, Rogers KW, Kozmikova I, Racioppi C, Brombacher EC, Czarkwiani A, Knapp D, Burger S, Chiavacci E, Shah G, Burger A, Huisken J, Yun MH, Christiaen L, Kozmik Z, Müller P, Bronner M, Krumlauf R, Mosimann C. Prummel KD, et al. Nat Commun. 2019 Aug 26;10(1):3857. doi: 10.1038/s41467-019-11561-7. Nat Commun. 2019. PMID: 31451684 Free PMC article.
Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.
Cantù C, Felker A, Zimmerli D, Prummel KD, Cabello EM, Chiavacci E, Méndez-Acevedo KM, Kirchgeorg L, Burger S, Ripoll J, Valenta T, Hausmann G, Vilain N, Aguet M, Burger A, Panáková D, Basler K, Mosimann C. Cantù C, et al. Among authors: prummel kd. Genes Dev. 2018 Nov 1;32(21-22):1443-1458. doi: 10.1101/gad.315531.118. Epub 2018 Oct 26. Genes Dev. 2018. PMID: 30366904 Free PMC article.