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Genome-wide CRISPR/Cas9 screen shows that loss of GET4 increases mitochondria-endoplasmic reticulum contact sites and is neuroprotective.
Wilson EL, Yu Y, Leal NS, Woodward JA, Patikas N, Morris JL, Field SF, Plumbly W, Paupe V, Chowdhury SR, Antrobus R, Lindop GE, Adia YM, Loh SHY, Prudent J, Martins LM, Metzakopian E. Wilson EL, et al. Among authors: prudent j. Cell Death Dis. 2024 Mar 11;15(3):203. doi: 10.1038/s41419-024-06568-y. Cell Death Dis. 2024. PMID: 38467609 Free PMC article.
The Complex Dance of Organelles during Mitochondrial Division.
Tábara LC, Morris JL, Prudent J. Tábara LC, et al. Among authors: prudent j. Trends Cell Biol. 2021 Apr;31(4):241-253. doi: 10.1016/j.tcb.2020.12.005. Epub 2021 Jan 11. Trends Cell Biol. 2021. PMID: 33446409 Free article. Review.
Mitochondrial dynamics: overview of molecular mechanisms.
Tilokani L, Nagashima S, Paupe V, Prudent J. Tilokani L, et al. Among authors: prudent j. Essays Biochem. 2018 Jul 20;62(3):341-360. doi: 10.1042/EBC20170104. Print 2018 Jul 20. Essays Biochem. 2018. PMID: 30030364 Free PMC article. Review.
AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology.
Tilokani L, Russell FM, Hamilton S, Virga DM, Segawa M, Paupe V, Gruszczyk AV, Protasoni M, Tabara LC, Johnson M, Anand H, Murphy MP, Hardie DG, Polleux F, Prudent J. Tilokani L, et al. Among authors: prudent j. Sci Adv. 2022 Nov 11;8(45):eabo7956. doi: 10.1126/sciadv.abo7956. Epub 2022 Nov 11. Sci Adv. 2022. PMID: 36367943 Free PMC article.
Mitochondrial matrix-localized Src kinase regulates mitochondrial morphology.
Lurette O, Guedouari H, Morris JL, Martín-Jiménez R, Robichaud JP, Hamel-Côté G, Khan M, Dauphinee N, Pichaud N, Prudent J, Hebert-Chatelain E. Lurette O, et al. Among authors: prudent j. Cell Mol Life Sci. 2022 May 30;79(6):327. doi: 10.1007/s00018-022-04325-y. Cell Mol Life Sci. 2022. PMID: 35637383 Free PMC article.
Fumarate induces vesicular release of mtDNA to drive innate immunity.
Zecchini V, Paupe V, Herranz-Montoya I, Janssen J, Wortel IMN, Morris JL, Ferguson A, Chowdury SR, Segarra-Mondejar M, Costa ASH, Pereira GC, Tronci L, Young T, Nikitopoulou E, Yang M, Bihary D, Caicci F, Nagashima S, Speed A, Bokea K, Baig Z, Samarajiwa S, Tran M, Mitchell T, Johnson M, Prudent J, Frezza C. Zecchini V, et al. Among authors: prudent j. Nature. 2023 Mar;615(7952):499-506. doi: 10.1038/s41586-023-05770-w. Epub 2023 Mar 8. Nature. 2023. PMID: 36890229 Free PMC article.
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