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Spiro-β-lactam BSS-730A Displays Potent Activity against HIV and Plasmodium.
Bártolo I, Santos BS, Fontinha D, Machado M, Francisco D, Sepodes B, Rocha J, Mota-Filipe H, Pinto R, Figueira ME, Barroso H, Nascimento T, Alves de Matos AP, Alves AJS, Alves NG, Simões CJV, Prudêncio M, Pinho E Melo TMVD, Taveira N. Bártolo I, et al. Among authors: prudencio m. ACS Infect Dis. 2021 Feb 12;7(2):421-434. doi: 10.1021/acsinfecdis.0c00768. Epub 2021 Jan 4. ACS Infect Dis. 2021. PMID: 33395253
Quinolin-4(1H)-imines are potent antiplasmodial drugs targeting the liver stage of malaria.
Rodrigues T, da Cruz FP, Lafuente-Monasterio MJ, Gonçalves D, Ressurreição AS, Sitoe AR, Bronze MR, Gut J, Schneider G, Mota MM, Rosenthal PJ, Prudêncio M, Gamo FJ, Lopes F, Moreira R. Rodrigues T, et al. Among authors: prudencio m. J Med Chem. 2013 Jun 13;56(11):4811-5. doi: 10.1021/jm400246e. Epub 2013 May 23. J Med Chem. 2013. PMID: 23701465
Tetraoxane-pyrimidine nitrile hybrids as dual stage antimalarials.
Oliveira R, Guedes RC, Meireles P, Albuquerque IS, Gonçalves LM, Pires E, Bronze MR, Gut J, Rosenthal PJ, Prudêncio M, Moreira R, O'Neill PM, Lopes F. Oliveira R, et al. Among authors: prudencio m. J Med Chem. 2014 Jun 12;57(11):4916-23. doi: 10.1021/jm5004528. Epub 2014 May 22. J Med Chem. 2014. PMID: 24824551
241 results