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4,9-Diaminoacridines and 4-Aminoacridines as Dual-Stage Antiplasmodial Hits.
Fonte M, Tassi N, Fontinha D, Bouzón-Arnáiz I, Ferraz R, Araújo MJ, Fernàndez-Busquets X, Prudêncio M, Gomes P, Teixeira C. Fonte M, et al. Among authors: prudencio m. ChemMedChem. 2021 Mar 3;16(5):788-792. doi: 10.1002/cmdc.202000740. Epub 2020 Dec 7. ChemMedChem. 2021. PMID: 33217195
Imidazoquines as antimalarial and antipneumocystis agents.
Vale N, Prudêncio M, Marques CA, Collins MS, Gut J, Nogueira F, Matos J, Rosenthal PJ, Cushion MT, do Rosário VE, Mota MM, Moreira R, Gomes P. Vale N, et al. Among authors: prudencio m. J Med Chem. 2009 Dec 10;52(23):7800-7. doi: 10.1021/jm900738c. J Med Chem. 2009. PMID: 19799426 Free PMC article.
Novel potent metallocenes against liver stage malaria.
Matos J, da Cruz FP, Cabrita É, Gut J, Nogueira F, do Rosário VE, Moreira R, Rosenthal PJ, Prudêncio M, Gomes P. Matos J, et al. Among authors: prudencio m. Antimicrob Agents Chemother. 2012 Mar;56(3):1564-70. doi: 10.1128/AAC.05345-11. Epub 2011 Dec 12. Antimicrob Agents Chemother. 2012. PMID: 22155838 Free PMC article.
N-cinnamoylated chloroquine analogues as dual-stage antimalarial leads.
Pérez BC, Teixeira C, Albuquerque IS, Gut J, Rosenthal PJ, Gomes JR, Prudêncio M, Gomes P. Pérez BC, et al. Among authors: prudencio m. J Med Chem. 2013 Jan 24;56(2):556-67. doi: 10.1021/jm301654b. Epub 2013 Jan 8. J Med Chem. 2013. PMID: 23273038 Free article.
Flavones as isosteres of 4(1H)-quinolones: discovery of ligand efficient and dual stage antimalarial lead compounds.
Rodrigues T, Ressurreição AS, da Cruz FP, Albuquerque IS, Gut J, Carrasco MP, Gonçalves D, Guedes RC, dos Santos DJ, Mota MM, Rosenthal PJ, Moreira R, Prudêncio M, Lopes F. Rodrigues T, et al. Among authors: prudencio m. Eur J Med Chem. 2013 Nov;69:872-80. doi: 10.1016/j.ejmech.2013.09.008. Epub 2013 Sep 20. Eur J Med Chem. 2013. PMID: 24125849
Tetraoxane-pyrimidine nitrile hybrids as dual stage antimalarials.
Oliveira R, Guedes RC, Meireles P, Albuquerque IS, Gonçalves LM, Pires E, Bronze MR, Gut J, Rosenthal PJ, Prudêncio M, Moreira R, O'Neill PM, Lopes F. Oliveira R, et al. Among authors: prudencio m. J Med Chem. 2014 Jun 12;57(11):4916-23. doi: 10.1021/jm5004528. Epub 2014 May 22. J Med Chem. 2014. PMID: 24824551
241 results