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Pliability in the m6A-Binding Region Extends Druggability of YTH Domains.
Cazzanelli G, Dalle Vedove A, Spagnolli G, Terruzzi L, Colasurdo E, Boldrini A, Patsilinakos A, Sturlese M, Grottesi A, Biasini E, Provenzani A, Quattrone A, Lolli G. Cazzanelli G, et al. Among authors: provenzani a. J Chem Inf Model. 2024 Mar 11;64(5):1682-1690. doi: 10.1021/acs.jcim.4c00051. Epub 2024 Feb 28. J Chem Inf Model. 2024. PMID: 38417111
Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6-Methyladenosine-Modified RNAs.
Micaelli M, Dalle Vedove A, Cerofolini L, Vigna J, Sighel D, Zaccara S, Bonomo I, Poulentzas G, Rosatti EF, Cazzanelli G, Alunno L, Belli R, Peroni D, Dassi E, Murakami S, Jaffrey SR, Fragai M, Mancini I, Lolli G, Quattrone A, Provenzani A. Micaelli M, et al. Among authors: provenzani a. ACS Pharmacol Transl Sci. 2022 Sep 14;5(10):872-891. doi: 10.1021/acsptsci.2c00008. eCollection 2022 Oct 14. ACS Pharmacol Transl Sci. 2022. PMID: 36268123 Free PMC article.
mRNA fate: Life and death of the mRNA in the cytoplasm.
Denti MA, Viero G, Provenzani A, Quattrone A, Macchi P. Denti MA, et al. Among authors: provenzani a. RNA Biol. 2013 Mar;10(3):360-6. doi: 10.4161/rna.23770. Epub 2013 Mar 1. RNA Biol. 2013. PMID: 23466755 Free PMC article.
Multilayer and MATR3-dependent regulation of mRNAs maintains pluripotency in human induced pluripotent stem cells.
Pollini D, Loffredo R, Maniscalco F, Cardano M, Micaelli M, Bonomo I, Licata NV, Peroni D, Tomaszewska W, Rossi A, Crippa V, Dassi E, Viero G, Quattrone A, Poletti A, Conti L, Provenzani A. Pollini D, et al. Among authors: provenzani a. iScience. 2021 Feb 16;24(3):102197. doi: 10.1016/j.isci.2021.102197. eCollection 2021 Mar 19. iScience. 2021. PMID: 33733063 Free PMC article.
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors.
Manzoni L, Zucal C, Maio DD, D'Agostino VG, Thongon N, Bonomo I, Lal P, Miceli M, Baj V, Brambilla M, Cerofolini L, Elezgarai S, Biasini E, Luchinat C, Novellino E, Fragai M, Marinelli L, Provenzani A, Seneci P. Manzoni L, et al. Among authors: provenzani a. J Med Chem. 2018 Feb 22;61(4):1483-1498. doi: 10.1021/acs.jmedchem.7b01176. Epub 2018 Jan 31. J Med Chem. 2018. PMID: 29313684
99 results