Proudfoot AEI - Search Results

1

A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.

Lee AW, Deruaz M, Lynch C, Davies G, Singh K, Alenazi Y, Eaton JRO, Kawamura A, Shaw J, Proudfoot AEI, Dias JM, Bhattacharya S. Lee AW, et al. Among authors: proudfoot aei. J Biol Chem. 2019 Jul 19;294(29):11199-11212. doi: 10.1074/jbc.RA119.008817. Epub 2019 Jun 5. J Biol Chem. 2019. PMID: 31167786 Free PMC article.

2

Evasins: Tick Salivary Proteins that Inhibit Mammalian Chemokines.

Bhusal RP, Eaton JRO, Chowdhury ST, Power CA, Proudfoot AEI, Stone MJ, Bhattacharya S. Bhusal RP, et al. Among authors: proudfoot aei. Trends Biochem Sci. 2020 Feb;45(2):108-122. doi: 10.1016/j.tibs.2019.10.003. Epub 2019 Nov 1. Trends Biochem Sci. 2020. PMID: 31679840 Free PMC article. Review.

3

Molecular cloning and characterization of a highly selective chemokine-binding protein from the tick Rhipicephalus sanguineus.

Frauenschuh A, Power CA, Déruaz M, Ferreira BR, Silva JS, Teixeira MM, Dias JM, Martin T, Wells TNC, Proudfoot AEI. Frauenschuh A, et al. Among authors: proudfoot aei. J Biol Chem. 2007 Sep 14;282(37):27250-27258. doi: 10.1074/jbc.M704706200. Epub 2007 Jul 19. J Biol Chem. 2007. PMID: 17640866 Free article.

4

Ticks produce highly selective chemokine binding proteins with antiinflammatory activity.

Déruaz M, Frauenschuh A, Alessandri AL, Dias JM, Coelho FM, Russo RC, Ferreira BR, Graham GJ, Shaw JP, Wells TN, Teixeira MM, Power CA, Proudfoot AE. Déruaz M, et al. J Exp Med. 2008 Sep 1;205(9):2019-31. doi: 10.1084/jem.20072689. Epub 2008 Aug 4. J Exp Med. 2008. PMID: 18678732 Free PMC article.

5

Structural basis of chemokine sequestration by a tick chemokine binding protein: the crystal structure of the complex between Evasin-1 and CCL3.

Dias JM, Losberger C, Déruaz M, Power CA, Proudfoot AE, Shaw JP. Dias JM, et al. PLoS One. 2009 Dec 30;4(12):e8514. doi: 10.1371/journal.pone.0008514. PLoS One. 2009. PMID: 20041127 Free PMC article.

6

Evasin-4, a tick-derived chemokine-binding protein with broad selectivity can be modified for use in preclinical disease models.

Déruaz M, Bonvin P, Severin IC, Johnson Z, Krohn S, Power CA, Proudfoot AE. Déruaz M, et al. FEBS J. 2013 Oct;280(19):4876-87. doi: 10.1111/febs.12463. Epub 2013 Aug 23. FEBS J. 2013. PMID: 23910450 Free PMC article.

7

Identification of the pharmacophore of the CC chemokine-binding proteins Evasin-1 and -4 using phage display.

Bonvin P, Dunn SM, Rousseau F, Dyer DP, Shaw J, Power CA, Handel TM, Proudfoot AEI. Bonvin P, et al. Among authors: proudfoot aei. J Biol Chem. 2014 Nov 14;289(46):31846-31855. doi: 10.1074/jbc.M114.599233. Epub 2014 Sep 29. J Biol Chem. 2014. PMID: 25266725 Free PMC article.

8

Chemokine blockers--therapeutics in the making?

Wells TN, Power CA, Shaw JP, Proudfoot AE. Wells TN, et al. Trends Pharmacol Sci. 2006 Jan;27(1):41-7. doi: 10.1016/j.tips.2005.11.001. Epub 2005 Nov 28. Trends Pharmacol Sci. 2006. PMID: 16310864 Review.

9

The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity.

Proudfoot AE, Fritchley S, Borlat F, Shaw JP, Vilbois F, Zwahlen C, Trkola A, Marchant D, Clapham PR, Wells TN. Proudfoot AE, et al. J Biol Chem. 2001 Apr 6;276(14):10620-6. doi: 10.1074/jbc.M010867200. Epub 2000 Dec 14. J Biol Chem. 2001. PMID: 11116158 Free article.

10

An engineered monomer of CCL2 has anti-inflammatory properties emphasizing the importance of oligomerization for chemokine activity in vivo.

Handel TM, Johnson Z, Rodrigues DH, Dos Santos AC, Cirillo R, Muzio V, Riva S, Mack M, Déruaz M, Borlat F, Vitte PA, Wells TN, Teixeira MM, Proudfoot AE. Handel TM, et al. J Leukoc Biol. 2008 Oct;84(4):1101-8. doi: 10.1189/jlb.0108061. Epub 2008 Jul 28. J Leukoc Biol. 2008. PMID: 18662971 Free PMC article.

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