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Exposure to nonmicrobial N-glycolylneuraminic acid protects farmers' children against airway inflammation and colitis.
Frei R, Ferstl R, Roduit C, Ziegler M, Schiavi E, Barcik W, Rodriguez-Perez N, Wirz OF, Wawrzyniak M, Pugin B, Nehrbass D, Jutel M, Smolinska S, Konieczna P, Bieli C, Loeliger S, Waser M, Pershagen G, Riedler J, Depner M, Schaub B, Genuneit J, Renz H, Pekkanen J, Karvonen AM, Dalphin JC, van Hage M, Doekes G, Akdis M, Braun-Fahrländer C, Akdis CA, von Mutius E, O'Mahony L, Lauener RP; Prevention of Allergy Risk factors for Sensitization in Children Related to Farming and Anthroposophic Lifestyle (PARSIFAL) study group; Protection Against Allergy Study in Rural Environments (PASTURE)/Mechanisms of Early Protective Exposures on Allergy Development (EFRAIM) study group. Frei R, et al. J Allergy Clin Immunol. 2018 Jan;141(1):382-390.e7. doi: 10.1016/j.jaci.2017.04.051. Epub 2017 Jun 17. J Allergy Clin Immunol. 2018. PMID: 28629745 Free article.
BACKGROUND: Childhood exposure to a farm environment has been shown to protect against the development of inflammatory diseases, such as allergy, asthma, and inflammatory bowel disease. ...METHODS: Exposure to Neu5Gc was evaluated by quan …
BACKGROUND: Childhood exposure to a farm environment has been shown to protect against the development of inflam …
Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood.
Lluis A, Depner M, Gaugler B, Saas P, Casaca VI, Raedler D, Michel S, Tost J, Liu J, Genuneit J, Pfefferle P, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Lauener R, Vuitton DA, Dalphin JC, Pekkanen J, von Mutius E, Schaub B; Protection Against Allergy: Study in Rural Environments Study Group. Lluis A, et al. J Allergy Clin Immunol. 2014 Feb;133(2):551-9. doi: 10.1016/j.jaci.2013.06.034. Epub 2013 Aug 28. J Allergy Clin Immunol. 2014. PMID: 23993223
OBJECTIVE: We sought to assess whether Treg cells from 4.5-year-old children from the Protection against Allergy: Study in Rural Environments birth cohort study are critical in the atopy and asthma-protective effect of farm expo …
OBJECTIVE: We sought to assess whether Treg cells from 4.5-year-old children from the Protection against Allergy: Study …