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Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape.
Reinisch I, Michenthaler H, Sulaj A, Moyschewitz E, Krstic J, Galhuber M, Xu R, Riahi Z, Wang T, Vujic N, Amor M, Zenezini Chiozzi R, Wabitsch M, Kolb D, Georgiadi A, Glawitsch L, Heitzer E, Schulz TJ, Schupp M, Sun W, Dong H, Ghosh A, Hoffmann A, Kratky D, Hinte LC, von Meyenn F, Heck AJR, Blüher M, Herzig S, Wolfrum C, Prokesch A. Reinisch I, et al. Among authors: prokesch a. Nat Commun. 2024 Feb 15;15(1):1391. doi: 10.1038/s41467-024-45724-y. Nat Commun. 2024. PMID: 38360943 Free PMC article.
NAT8L (N-acetyltransferase 8-like) accelerates lipid turnover and increases energy expenditure in brown adipocytes.
Pessentheiner AR, Pelzmann HJ, Walenta E, Schweiger M, Groschner LN, Graier WF, Kolb D, Uno K, Miyazaki T, Nitta A, Rieder D, Prokesch A, Bogner-Strauss JG. Pessentheiner AR, et al. Among authors: prokesch a. J Biol Chem. 2013 Dec 13;288(50):36040-51. doi: 10.1074/jbc.M113.491324. Epub 2013 Oct 23. J Biol Chem. 2013. PMID: 24155240 Free PMC article.
Characterization of rat serum amyloid A4 (SAA4): a novel member of the SAA superfamily.
Rossmann C, Windpassinger C, Brunner D, Kovacevic A, Schweighofer N, Malli R, Schuligoi R, Prokesch A, Kluve-Beckerman B, Graier WF, Kratky D, Sattler W, Malle E. Rossmann C, et al. Among authors: prokesch a. Biochem Biophys Res Commun. 2014 Aug 8;450(4):1643-9. doi: 10.1016/j.bbrc.2014.07.054. Epub 2014 Jul 17. Biochem Biophys Res Commun. 2014. PMID: 25044109 Free PMC article.
Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
Prokesch A, Graef FA, Madl T, Kahlhofer J, Heidenreich S, Schumann A, Moyschewitz E, Pristoynik P, Blaschitz A, Knauer M, Muenzner M, Bogner-Strauss JG, Dohr G, Schulz TJ, Schupp M. Prokesch A, et al. FASEB J. 2017 Feb;31(2):732-742. doi: 10.1096/fj.201600845R. Epub 2016 Nov 3. FASEB J. 2017. PMID: 27811061 Free PMC article.
Here we report a previously unrecognized role of the tumor suppressor p53 in the physiologic adaptation to food withdrawal. ...Because of its tumor suppressor function, p53 stabilization by starvation could have implications for both metabolic and oncological diseases of t …
Here we report a previously unrecognized role of the tumor suppressor p53 in the physiologic adaptation to food withdrawal. ...Becaus …
Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis.
Duta-Mare M, Sachdev V, Leopold C, Kolb D, Vujic N, Korbelius M, Hofer DC, Xia W, Huber K, Auer M, Gottschalk B, Magnes C, Graier WF, Prokesch A, Radovic B, Bogner-Strauss JG, Kratky D. Duta-Mare M, et al. Among authors: prokesch a. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Apr;1863(4):467-478. doi: 10.1016/j.bbalip.2018.01.011. Epub 2018 Jan 31. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 29374543 Free PMC article.
p53 Functions in Adipose Tissue Metabolism and Homeostasis.
Krstic J, Reinisch I, Schupp M, Schulz TJ, Prokesch A. Krstic J, et al. Among authors: prokesch a. Int J Mol Sci. 2018 Sep 4;19(9):2622. doi: 10.3390/ijms19092622. Int J Mol Sci. 2018. PMID: 30181511 Free PMC article. Review.
N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.
Huber K, Hofer DC, Trefely S, Pelzmann HJ, Madreiter-Sokolowski C, Duta-Mare M, Schlager S, Trausinger G, Stryeck S, Graier WF, Kolb D, Magnes C, Snyder NW, Prokesch A, Kratky D, Madl T, Wellen KE, Bogner-Strauss JG. Huber K, et al. Among authors: prokesch a. Biochim Biophys Acta Mol Cell Res. 2019 Mar;1866(3):337-348. doi: 10.1016/j.bbamcr.2018.08.017. Epub 2018 Aug 31. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30595160 Free PMC article.
51 results