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Cancer-associated miRNAs and their therapeutic potential.
Inoue J, Inazawa J. Inoue J, et al. J Hum Genet. 2021 Sep;66(9):937-945. doi: 10.1038/s10038-021-00938-6. Epub 2021 Jun 4. J Hum Genet. 2021. PMID: 34088973 Review.
Some miRNAs are closely involved in the development and progression of cancer and are abnormally expressed in many cancer types. Therefore, control of the expression of cancer-associated miRNAs is expected as a next-generation drug modality to treat advanced …
Some miRNAs are closely involved in the development and progression of cancer and are abnormally expressed in many cancer type …
p53-PHLDA3-Akt Network: The Key Regulators of Neuroendocrine Tumorigenesis.
Chen Y, Ohki R. Chen Y, et al. Int J Mol Sci. 2020 Jun 8;21(11):4098. doi: 10.3390/ijms21114098. Int J Mol Sci. 2020. PMID: 32521808 Free PMC article. Review.
p53 is a well-known tumor suppressor gene and one of the most extensively studied genes in cancer research. p53 functions largely as a transcription factor and can trigger a variety of antiproliferative programs via induction of its target genes. ...
p53 is a well-known tumor suppressor gene and one of the most extensively studied genes in cancer research. p53 functions larg …