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A comprehensive mechanism of fibrin network formation involving early branching and delayed single- to double-strand transition from coupled time-resolved X-ray/light-scattering detection.
Rocco M, Molteni M, Ponassi M, Giachi G, Frediani M, Koutsioubas A, Profumo A, Trevarin D, Cardinali B, Vachette P, Ferri F, Pérez J. Rocco M, et al. Among authors: profumo a. J Am Chem Soc. 2014 Apr 9;136(14):5376-84. doi: 10.1021/ja5002955. Epub 2014 Apr 1. J Am Chem Soc. 2014. PMID: 24654923
Early events in the polymerization of fibrin.
Rocco M, Bernocco S, Turci M, Profumo A, Cuniberti C, Ferri F. Rocco M, et al. Among authors: profumo a. Ann N Y Acad Sci. 2001;936:167-84. doi: 10.1111/j.1749-6632.2001.tb03504.x. Ann N Y Acad Sci. 2001. PMID: 11460473
Substitution of the human αC region with the analogous chicken domain generates a fibrinogen with severely impaired lateral aggregation: fibrin monomers assemble into protofibrils but protofibrils do not assemble into fibers.
Ping L, Huang L, Cardinali B, Profumo A, Gorkun OV, Lord ST. Ping L, et al. Among authors: profumo a. Biochemistry. 2011 Oct 25;50(42):9066-75. doi: 10.1021/bi201094v. Epub 2011 Sep 27. Biochemistry. 2011. PMID: 21932842 Free PMC article.
Hydrodynamic characterization of recombinant human fibrinogen species.
Raynal B, Cardinali B, Grimbergen J, Profumo A, Lord ST, England P, Rocco M. Raynal B, et al. Among authors: profumo a. Thromb Res. 2013 Jul;132(1):e48-53. doi: 10.1016/j.thromres.2013.04.005. Epub 2013 Apr 30. Thromb Res. 2013. PMID: 23642654 Free PMC article.
156 results