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Alginate oligosaccharides inhibit fungal cell growth and potentiate the activity of antifungals against Candida and Aspergillus spp.
Tøndervik A, Sletta H, Klinkenberg G, Emanuel C, Powell LC, Pritchard MF, Khan S, Craine KM, Onsøyen E, Rye PD, Wright C, Thomas DW, Hill KE. Tøndervik A, et al. Among authors: pritchard mf. PLoS One. 2014 Nov 19;9(11):e112518. doi: 10.1371/journal.pone.0112518. eCollection 2014. PLoS One. 2014. PMID: 25409186 Free PMC article.
A New Class of Safe Oligosaccharide Polymer Therapy To Modify the Mucus Barrier of Chronic Respiratory Disease.
Pritchard MF, Powell LC, Menzies GE, Lewis PD, Hawkins K, Wright C, Doull I, Walsh TR, Onsøyen E, Dessen A, Myrvold R, Rye PD, Myrset AH, Stevens HN, Hodges LA, MacGregor G, Neilly JB, Hill KE, Thomas DW. Pritchard MF, et al. Mol Pharm. 2016 Mar 7;13(3):863-72. doi: 10.1021/acs.molpharmaceut.5b00794. Epub 2016 Feb 16. Mol Pharm. 2016. PMID: 26833139 Free article.
Alginate Oligosaccharide-Induced Modification of the lasI-lasR and rhlI-rhlR Quorum-Sensing Systems in Pseudomonas aeruginosa.
Jack AA, Khan S, Powell LC, Pritchard MF, Beck K, Sadh H, Sutton L, Cavaliere A, Florance H, Rye PD, Thomas DW, Hill KE. Jack AA, et al. Among authors: pritchard mf. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02318-17. doi: 10.1128/AAC.02318-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29463534 Free PMC article.
Targeted disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate oligosaccharides.
Powell LC, Pritchard MF, Ferguson EL, Powell KA, Patel SU, Rye PD, Sakellakou SM, Buurma NJ, Brilliant CD, Copping JM, Menzies GE, Lewis PD, Hill KE, Thomas DW. Powell LC, et al. Among authors: pritchard mf. NPJ Biofilms Microbiomes. 2018 Jun 29;4:13. doi: 10.1038/s41522-018-0056-3. eCollection 2018. NPJ Biofilms Microbiomes. 2018. PMID: 29977590 Free PMC article.
20 results