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Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth.
Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, Shikatani EA, El-Maklizi M, Williams JW, Robins L, Li C, Lewis B, Yun TJ, Lee JS, Wieghofer P, Khattar R, Farrokhi K, Byrne J, Ouzounian M, Zavitz CC, Levy GA, Bauer CM, Libby P, Husain M, Swirski FK, Cheong C, Prinz M, Hilgendorf I, Randolph GJ, Epelman S, Gramolini AO, Cybulsky MI, Rubin BB, Robbins CS. Ensan S, et al. Among authors: prinz m. Nat Immunol. 2016 Feb;17(2):159-68. doi: 10.1038/ni.3343. Epub 2015 Dec 7. Nat Immunol. 2016. PMID: 26642357
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways.
Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, Wieghofer P, Heinrich A, Riemke P, Hölscher C, Müller DN, Luckow B, Brocker T, Debowski K, Fritz G, Opdenakker G, Diefenbach A, Biber K, Heikenwalder M, Geissmann F, Rosenbauer F, Prinz M. Kierdorf K, et al. Among authors: prinz m. Nat Neurosci. 2013 Mar;16(3):273-80. doi: 10.1038/nn.3318. Epub 2013 Jan 20. Nat Neurosci. 2013. PMID: 23334579
Genetic targeting of microglia.
Wieghofer P, Knobeloch KP, Prinz M. Wieghofer P, et al. Among authors: prinz m. Glia. 2015 Jan;63(1):1-22. doi: 10.1002/glia.22727. Epub 2014 Aug 8. Glia. 2015. PMID: 25132502 Review.
Progressive replacement of embryo-derived cardiac macrophages with age.
Molawi K, Wolf Y, Kandalla PK, Favret J, Hagemeyer N, Frenzel K, Pinto AR, Klapproth K, Henri S, Malissen B, Rodewald HR, Rosenthal NA, Bajenoff M, Prinz M, Jung S, Sieweke MH. Molawi K, et al. Among authors: prinz m. J Exp Med. 2014 Oct 20;211(11):2151-8. doi: 10.1084/jem.20140639. Epub 2014 Sep 22. J Exp Med. 2014. PMID: 25245760 Free PMC article.
Host microbiota constantly control maturation and function of microglia in the CNS.
Erny D, Hrabě de Angelis AL, Jaitin D, Wieghofer P, Staszewski O, David E, Keren-Shaul H, Mahlakoiv T, Jakobshagen K, Buch T, Schwierzeck V, Utermöhlen O, Chun E, Garrett WS, McCoy KD, Diefenbach A, Staeheli P, Stecher B, Amit I, Prinz M. Erny D, et al. Among authors: prinz m. Nat Neurosci. 2015 Jul;18(7):965-77. doi: 10.1038/nn.4030. Epub 2015 Jun 1. Nat Neurosci. 2015. PMID: 26030851 Free PMC article.
671 results