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Type III-B CRISPR-Cas cascade of proteolytic cleavages.
Science. 2024 Feb 2;383(6682):512-519. doi: 10.1126/science.adk0378. Epub 2024 Feb 1.
Science. 2024.
PMID: 38301007
SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation.
Steens JA, Zhu Y, Taylor DW, Bravo JPK, Prinsen SHP, Schoen CD, Keijser BJF, Ossendrijver M, Hofstra LM, Brouns SJJ, Shinkai A, van der Oost J, Staals RHJ.
Steens JA, et al. Among authors: prinsen shp.
Nat Commun. 2021 Aug 19;12(1):5033. doi: 10.1038/s41467-021-25337-5.
Nat Commun. 2021.
PMID: 34413302
Free PMC article.
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The miniature CRISPR-Cas12m effector binds DNA to block transcription.
Wu WY, Mohanraju P, Liao C, Adiego-Pérez B, Creutzburg SCA, Makarova KS, Keessen K, Lindeboom TA, Khan TS, Prinsen S, Joosten R, Yan WX, Migur A, Laffeber C, Scott DA, Lebbink JHG, Koonin EV, Beisel CL, van der Oost J.
Wu WY, et al.
Mol Cell. 2022 Dec 1;82(23):4487-4502.e7. doi: 10.1016/j.molcel.2022.11.003. Epub 2022 Nov 24.
Mol Cell. 2022.
PMID: 36427491
Free article.
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