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Regulation and function of the human HSP90AA1 gene.
Zuehlke AD, Beebe K, Neckers L, Prince T. Zuehlke AD, et al. Gene. 2015 Oct 1;570(1):8-16. doi: 10.1016/j.gene.2015.06.018. Epub 2015 Jun 10. Gene. 2015. PMID: 26071189 Free PMC article. Review.
Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.
Sattin S, Tao J, Vettoretti G, Moroni E, Pennati M, Lopergolo A, Morelli L, Bugatti A, Zuehlke A, Moses M, Prince T, Kijima T, Beebe K, Rusnati M, Neckers L, Zaffaroni N, Agard DA, Bernardi A, Colombo G. Sattin S, et al. Chemistry. 2015 Sep 21;21(39):13598-608. doi: 10.1002/chem.201502211. Epub 2015 Aug 18. Chemistry. 2015. PMID: 26286886 Free PMC article.
Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors.
Mollapour M, Bourboulia D, Beebe K, Woodford MR, Polier S, Hoang A, Chelluri R, Li Y, Guo A, Lee MJ, Fotooh-Abadi E, Khan S, Prince T, Miyajima N, Yoshida S, Tsutsumi S, Xu W, Panaretou B, Stetler-Stevenson WG, Bratslavsky G, Trepel JB, Prodromou C, Neckers L. Mollapour M, et al. Mol Cell. 2014 Jan 23;53(2):317-29. doi: 10.1016/j.molcel.2013.12.007. Mol Cell. 2014. PMID: 24462205 Free PMC article.
Targeting the oncogene and kinome chaperone CDC37.
Gray PJ Jr, Prince T, Cheng J, Stevenson MA, Calderwood SK. Gray PJ Jr, et al. Nat Rev Cancer. 2008 Jul;8(7):491-5. doi: 10.1038/nrc2420. Epub 2008 May 30. Nat Rev Cancer. 2008. PMID: 18511936 Free PMC article. Review.
36 results