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MitoNeoD: A Mitochondria-Targeted Superoxide Probe.
Shchepinova MM, Cairns AG, Prime TA, Logan A, James AM, Hall AR, Vidoni S, Arndt S, Caldwell ST, Prag HA, Pell VR, Krieg T, Mulvey JF, Yadav P, Cobley JN, Bright TP, Senn HM, Anderson RF, Murphy MP, Hartley RC. Shchepinova MM, et al. Among authors: prime ta. Cell Chem Biol. 2017 Oct 19;24(10):1285-1298.e12. doi: 10.1016/j.chembiol.2017.08.003. Epub 2017 Sep 7. Cell Chem Biol. 2017. PMID: 28890317 Free PMC article.
Accumulation of lipophilic dications by mitochondria and cells.
Ross MF, Da Ros T, Blaikie FH, Prime TA, Porteous CM, Severina II, Skulachev VP, Kjaergaard HG, Smith RA, Murphy MP. Ross MF, et al. Among authors: prime ta. Biochem J. 2006 Nov 15;400(1):199-208. doi: 10.1042/BJ20060919. Biochem J. 2006. PMID: 16948637 Free PMC article.
Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa subunit: potential role of CYS residues in decreasing oxidative damage.
Hurd TR, Requejo R, Filipovska A, Brown S, Prime TA, Robinson AJ, Fearnley IM, Murphy MP. Hurd TR, et al. Among authors: prime ta. J Biol Chem. 2008 Sep 5;283(36):24801-15. doi: 10.1074/jbc.M803432200. Epub 2008 Jul 8. J Biol Chem. 2008. PMID: 18611857 Free PMC article.
Mitochondria-targeted antioxidants in the treatment of disease.
Smith RA, Adlam VJ, Blaikie FH, Manas AR, Porteous CM, James AM, Ross MF, Logan A, Cochemé HM, Trnka J, Prime TA, Abakumova I, Jones BA, Filipovska A, Murphy MP. Smith RA, et al. Among authors: prime ta. Ann N Y Acad Sci. 2008 Dec;1147:105-11. doi: 10.1196/annals.1427.003. Ann N Y Acad Sci. 2008. PMID: 19076435 Review.
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury.
Prime TA, Blaikie FH, Evans C, Nadtochiy SM, James AM, Dahm CC, Vitturi DA, Patel RP, Hiley CR, Abakumova I, Requejo R, Chouchani ET, Hurd TR, Garvey JF, Taylor CT, Brookes PS, Smith RA, Murphy MP. Prime TA, et al. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10764-9. doi: 10.1073/pnas.0903250106. Epub 2009 Jun 15. Proc Natl Acad Sci U S A. 2009. PMID: 19528654 Free PMC article.
Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice.
Rodriguez-Cuenca S, Cochemé HM, Logan A, Abakumova I, Prime TA, Rose C, Vidal-Puig A, Smith AC, Rubinsztein DC, Fearnley IM, Jones BA, Pope S, Heales SJ, Lam BY, Neogi SG, McFarlane I, James AM, Smith RA, Murphy MP. Rodriguez-Cuenca S, et al. Among authors: prime ta. Free Radic Biol Med. 2010 Jan 1;48(1):161-72. doi: 10.1016/j.freeradbiomed.2009.10.039. Epub 2009 Oct 23. Free Radic Biol Med. 2010. PMID: 19854266
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix.
Cochemé HM, Quin C, McQuaker SJ, Cabreiro F, Logan A, Prime TA, Abakumova I, Patel JV, Fearnley IM, James AM, Porteous CM, Smith RA, Saeed S, Carré JE, Singer M, Gems D, Hartley RC, Partridge L, Murphy MP. Cochemé HM, et al. Among authors: prime ta. Cell Metab. 2011 Mar 2;13(3):340-50. doi: 10.1016/j.cmet.2011.02.003. Cell Metab. 2011. PMID: 21356523 Free PMC article.
41 results