Price LS - Search Results

1

Screening out irrelevant cell-based models of disease.

Horvath P, Aulner N, Bickle M, Davies AM, Nery ED, Ebner D, Montoya MC, Östling P, Pietiäinen V, Price LS, Shorte SL, Turcatti G, von Schantz C, Carragher NO. Horvath P, et al. Among authors: price ls. Nat Rev Drug Discov. 2016 Nov;15(11):751-769. doi: 10.1038/nrd.2016.175. Epub 2016 Sep 12. Nat Rev Drug Discov. 2016. PMID: 27616293 Review.

2

3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis.

Booij TH, Price LS, Danen EHJ. Booij TH, et al. Among authors: price ls. SLAS Discov. 2019 Jul;24(6):615-627. doi: 10.1177/2472555219830087. Epub 2019 Feb 28. SLAS Discov. 2019. PMID: 30817892 Free PMC article.

3

High-Throughput Phenotypic Screening of Kinase Inhibitors to Identify Drug Targets for Polycystic Kidney Disease.

Booij TH, Bange H, Leonhard WN, Yan K, Fokkelman M, Kunnen SJ, Dauwerse JG, Qin Y, van de Water B, van Westen GJP, Peters DJM, Price LS. Booij TH, et al. Among authors: price ls. SLAS Discov. 2017 Sep;22(8):974-984. doi: 10.1177/2472555217716056. Epub 2017 Jun 23. SLAS Discov. 2017. PMID: 28644734 Free PMC article.

4

Application of siRNA in targeting protein expression in kidney disease.

Stokman G, Qin Y, Rácz Z, Hamar P, Price LS. Stokman G, et al. Among authors: price ls. Adv Drug Deliv Rev. 2010 Nov 30;62(14):1378-89. doi: 10.1016/j.addr.2010.07.005. Epub 2010 Jul 25. Adv Drug Deliv Rev. 2010. PMID: 20667456 Review.

5

Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling.

Sandercock AM, Rust S, Guillard S, Sachsenmeier KF, Holoweckyj N, Hay C, Flynn M, Huang Q, Yan K, Herpers B, Price LS, Soden J, Freeth J, Jermutus L, Hollingsworth R, Minter R. Sandercock AM, et al. Among authors: price ls. Mol Cancer. 2015 Jul 31;14:147. doi: 10.1186/s12943-015-0415-0. Mol Cancer. 2015. PMID: 26227951 Free PMC article.

6

Development of a 3D Tissue Culture-Based High-Content Screening Platform That Uses Phenotypic Profiling to Discriminate Selective Inhibitors of Receptor Tyrosine Kinases.

Booij TH, Klop MJ, Yan K, Szántai-Kis C, Szokol B, Orfi L, van de Water B, Keri G, Price LS. Booij TH, et al. Among authors: price ls. J Biomol Screen. 2016 Oct;21(9):912-22. doi: 10.1177/1087057116657269. Epub 2016 Jul 7. J Biomol Screen. 2016. PMID: 27412535 Free PMC article.

7

A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies.

Ramaiahgari SC, den Braver MW, Herpers B, Terpstra V, Commandeur JN, van de Water B, Price LS. Ramaiahgari SC, et al. Among authors: price ls. Arch Toxicol. 2014 May;88(5):1083-95. doi: 10.1007/s00204-014-1215-9. Epub 2014 Mar 6. Arch Toxicol. 2014. PMID: 24599296

8

Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy.

Koedoot E, Wolters L, Smid M, Stoilov P, Burger GA, Herpers B, Yan K, Price LS, Martens JWM, Le Dévédec SE, van de Water B. Koedoot E, et al. Among authors: price ls. Sci Rep. 2021 Mar 31;11(1):7259. doi: 10.1038/s41598-021-86664-7. Sci Rep. 2021. PMID: 33790333 Free PMC article.

9

High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability.

Hiemstra S, Ramaiahgari SC, Wink S, Callegaro G, Coonen M, Meerman J, Jennen D, van den Nieuwendijk K, Dankers A, Snoeys J, de Bont H, Price L, van de Water B. Hiemstra S, et al. Arch Toxicol. 2019 Oct;93(10):2895-2911. doi: 10.1007/s00204-019-02552-0. Epub 2019 Aug 27. Arch Toxicol. 2019. PMID: 31552476

10

Ultra high content image analysis and phenotype profiling of 3D cultured micro-tissues.

Di Z, Klop MJ, Rogkoti VM, Le Dévédec SE, van de Water B, Verbeek FJ, Price LS, Meerman JH. Di Z, et al. Among authors: price ls. PLoS One. 2014 Oct 7;9(10):e109688. doi: 10.1371/journal.pone.0109688. eCollection 2014. PLoS One. 2014. PMID: 25289886 Free PMC article.

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