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Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis.
Fondevila MF, Fernandez U, Heras V, Parracho T, Gonzalez-Rellan MJ, Novoa E, Porteiro B, Alonso C, Mayo R, da Silva Lima N, Iglesias C, Filliol AA, Senra A, Delgado TC, Woodhoo A, Herrero L, Serra D, Prevot V, Schwaninger M, López M, Dieguez C, Millet O, Mato JM, Cubero FJ, Varela-Rey M, Iruzubieta P, Crespo J, Martinez-Chantar ML, Schwabe RF, Nogueiras R. Fondevila MF, et al. Among authors: prevot v. J Hepatol. 2022 Jul;77(1):15-28. doi: 10.1016/j.jhep.2022.02.003. Epub 2022 Feb 12. J Hepatol. 2022. PMID: 35167910 Free article.
MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance.
Al-Massadi O, Quiñones M, Clasadonte J, Hernandez-Bautista R, Romero-Picó A, Folgueira C, Morgan DA, Kalló I, Heras V, Senra A, Funderburk SC, Krashes MJ, Souto Y, Fidalgo M, Luquet S, Chee MJ, Imbernon M, Beiroa D, García-Caballero L, Gallego R, Lam BYH, Yeo G, Lopez M, Liposits Z, Rahmouni K, Prevot V, Dieguez C, Nogueiras R. Al-Massadi O, et al. Among authors: prevot v. Diabetes. 2019 Dec;68(12):2210-2222. doi: 10.2337/db19-0029. Epub 2019 Sep 16. Diabetes. 2019. PMID: 31530579 Free PMC article.
Hypothalamic dopamine signaling regulates brown fat thermogenesis.
Folgueira C, Beiroa D, Porteiro B, Duquenne M, Puighermanal E, Fondevila MF, Barja-Fernández S, Gallego R, Hernández-Bautista R, Castelao C, Senra A, Seoane P, Gómez N, Aguiar P, Guallar D, Fidalgo M, Romero-Pico A, Adan R, Blouet C, Labandeira-García JL, Jeanrenaud F, Kallo I, Liposits Z, Salvador J, Prevot V, Dieguez C, Lopez M, Valjent E, Frühbeck G, Seoane LM, Nogueiras R. Folgueira C, et al. Among authors: prevot v. Nat Metab. 2019 Aug;1(8):811-829. doi: 10.1038/s42255-019-0099-7. Epub 2019 Aug 19. Nat Metab. 2019. PMID: 31579887 Free PMC article.
Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points.
Fondevila MF, Mercado-Gómez M, Rodríguez A, Gonzalez-Rellan MJ, Iruzubieta P, Valentí V, Escalada J, Schwaninger M, Prevot V, Dieguez C, Crespo J, Frühbeck G, Martinez-Chantar ML, Nogueiras R. Fondevila MF, et al. Among authors: prevot v. J Hepatol. 2021 Feb;74(2):469-471. doi: 10.1016/j.jhep.2020.09.027. Epub 2020 Oct 20. J Hepatol. 2021. PMID: 33096086 Free PMC article. No abstract available.
Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner.
Quiñones M, Hernández-Bautista R, Beiroa D, Heras V, Torres-Leal FL, Lam BYH, Senra A, Fernø J, Gómez-Valadés AG, Schwaninger M, Prevot V, Yeo G, Claret M, López M, Diéguez C, Al-Massadi O, Nogueiras R. Quiñones M, et al. Among authors: prevot v. Redox Biol. 2021 May;41:101945. doi: 10.1016/j.redox.2021.101945. Epub 2021 Mar 13. Redox Biol. 2021. PMID: 33744652 Free PMC article.
Short regulatory DNA sequences to target brain endothelial cells for gene therapy.
Graßhoff H, Müller-Fielitz H, Dogbevia GK, Körbelin J, Bannach J, Vahldieck CM, Kusche-Vihrog K, Jöhren O, Müller OJ, Nogueiras R, Prevot V, Schwaninger M. Graßhoff H, et al. Among authors: prevot v. J Cereb Blood Flow Metab. 2022 Jan;42(1):104-120. doi: 10.1177/0271678X211039617. Epub 2021 Aug 24. J Cereb Blood Flow Metab. 2022. PMID: 34427142 Free PMC article.
Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function.
da Silva Lima N, Fondevila MF, Nóvoa E, Buqué X, Mercado-Gómez M, Gallet S, González-Rellan MJ, Fernandez U, Loyens A, Garcia-Vence M, Chantada-Vazquez MDP, Bravo SB, Marañon P, Senra A, Escudero A, Leiva M, Guallar D, Fidalgo M, Gomes P, Claret M, Sabio G, Varela-Rey M, Delgado TC, Montero-Vallejo R, Ampuero J, López M, Diéguez C, Herrero L, Serra D, Schwaninger M, Prevot V, Gallego-Duran R, Romero-Gomez M, Iruzubieta P, Crespo J, Martinez-Chantar ML, Garcia-Monzon C, Gonzalez-Rodriguez A, Aspichueta P, Nogueiras R. da Silva Lima N, et al. Among authors: prevot v. J Hepatol. 2022 Jan;76(1):11-24. doi: 10.1016/j.jhep.2021.09.008. Epub 2021 Sep 21. J Hepatol. 2022. PMID: 34555423 Free article.
263 results