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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 2
2002 1
2003 1
2004 2
2005 3
2006 1
2007 2
2008 4
2009 4
2010 4
2012 5
2013 7
2014 5
2015 7
2016 9
2017 8
2018 13
2019 3
2020 16
2021 20
2022 14
2023 15
2024 8

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139 results

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Page 1
Machine Learning for Early Lung Cancer Identification Using Routine Clinical and Laboratory Data.
Gould MK, Huang BZ, Tammemagi MC, Kinar Y, Shiff R. Gould MK, et al. Am J Respir Crit Care Med. 2021 Aug 15;204(4):445-453. doi: 10.1164/rccm.202007-2791OC. Am J Respir Crit Care Med. 2021. PMID: 33823116
Rationale: Most lung cancers are diagnosed at an advanced stage. Presymptomatic identification of high-risk individuals can prompt earlier intervention and improve long-term outcomes. ...Methods: We assembled data from 6,505 case patients with non-small cell lung cancer (N …
Rationale: Most lung cancers are diagnosed at an advanced stage. Presymptomatic identification of high-risk individuals can prompt ea …
Novel PET/SPECT probes for imaging of tau in Alzheimer's disease.
Watanabe H, Ono M, Saji H. Watanabe H, et al. ScientificWorldJournal. 2015;2015:124192. doi: 10.1155/2015/124192. Epub 2015 Mar 23. ScientificWorldJournal. 2015. PMID: 25879047 Free PMC article. Review.
Since the presence of NFTs is well correlated with neurodegeneration and cognitive decline in AD, imaging of tau using positron emission tomography (PET) and single-photon emission computed tomography (SPECT) is useful for presymptomatic diagnosis and monitoring of the pro …
Since the presence of NFTs is well correlated with neurodegeneration and cognitive decline in AD, imaging of tau using positron emission tom …
Open issues in Mucopolysaccharidosis type I-Hurler.
Parini R, Deodato F, Di Rocco M, Lanino E, Locatelli F, Messina C, Rovelli A, Scarpa M. Parini R, et al. Orphanet J Rare Dis. 2017 Jun 15;12(1):112. doi: 10.1186/s13023-017-0662-9. Orphanet J Rare Dis. 2017. PMID: 28619065 Free PMC article. Review.
Other strategies must then be considered to improve the outcome of these patients: one is to pursue early pre-symptomatic diagnosis through newborn screening and another one is the identification of novel treatments. In this perspective, even though newborn screening can b …
Other strategies must then be considered to improve the outcome of these patients: one is to pursue early pre-symptomatic diagnosis through …
Open science datasets from PREVENT-AD, a longitudinal cohort of pre-symptomatic Alzheimer's disease.
Tremblay-Mercier J, Madjar C, Das S, Pichet Binette A, Dyke SOM, Étienne P, Lafaille-Magnan ME, Remz J, Bellec P, Louis Collins D, Natasha Rajah M, Bohbot V, Leoutsakos JM, Iturria-Medina Y, Kat J, Hoge RD, Gauthier S, Tardif CL, Mallar Chakravarty M, Poline JB, Rosa-Neto P, Evans AC, Villeneuve S, Poirier J, Breitner JCS; PREVENT-AD Research Group. Tremblay-Mercier J, et al. Neuroimage Clin. 2021;31:102733. doi: 10.1016/j.nicl.2021.102733. Epub 2021 Jun 17. Neuroimage Clin. 2021. PMID: 34192666 Free PMC article.
We describe the creation of an open science dataset from the PREVENT-AD (PResymptomatic EValuation of Experimental or Novel Treatments for AD) cohort, composed of cognitively unimpaired older individuals with a parental or multiple-sibling history of AD. ...
We describe the creation of an open science dataset from the PREVENT-AD (PResymptomatic EValuation of Experimental or Novel …
Effectiveness of Contact Tracing for Viral Disease Mitigation and Suppression: Evidence-Based Review.
Thomas Craig KJ, Rizvi R, Willis VC, Kassler WJ, Jackson GP. Thomas Craig KJ, et al. JMIR Public Health Surveill. 2021 Oct 6;7(10):e32468. doi: 10.2196/32468. JMIR Public Health Surveill. 2021. PMID: 34612841 Free PMC article. Review.
Given the high transmissibility of SARS-CoV-2, short serial intervals, and asymptomatic transmission patterns, the effectiveness of contact tracing for this novel viral agent is largely unknown. OBJECTIVE: This study aims to identify and synthesize evidence regarding the e …
Given the high transmissibility of SARS-CoV-2, short serial intervals, and asymptomatic transmission patterns, the effectiveness of contact …
Discovery of Novel Markers for Identifying Cognitive Decline Using Neuron-Derived Exosomes.
Zhong J, Ren X, Liu W, Wang S, Lv Y, Nie L, Lin R, Tian X, Yang X, Zhu F, Liu J. Zhong J, et al. Front Aging Neurosci. 2021 Aug 26;13:696944. doi: 10.3389/fnagi.2021.696944. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34512304 Free PMC article.
Since there are few therapeutic options for symptomatic AD, research is increasingly focused on the identification of pre-symptomatic biomarkers. Recently, evaluation of neuron-derived exosomal markers has emerged as a promising novel approach for determining neuron …
Since there are few therapeutic options for symptomatic AD, research is increasingly focused on the identification of pre-symptomatic biomar …
Spatial Extent of Amyloid-β Levels and Associations With Tau-PET and Cognition.
Ozlen H, Pichet Binette A, Köbe T, Meyer PF, Gonneaud J, St-Onge F, Provost K, Soucy JP, Rosa-Neto P, Breitner J, Poirier J, Villeneuve S; Alzheimer’s Disease Neuroimaging Initiative, the Harvard Aging Brain Study, the Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer Disease Research Group. Ozlen H, et al. JAMA Neurol. 2022 Oct 1;79(10):1025-1035. doi: 10.1001/jamaneurol.2022.2442. JAMA Neurol. 2022. PMID: 35994280 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: This longitudinal multicentric cohort study included 3 independent cohorts: Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer Disease (PREVENT-AD) (data collected from 2012-2020), Alzheimer Disease …
DESIGN, SETTING, AND PARTICIPANTS: This longitudinal multicentric cohort study included 3 independent cohorts: Presymptomatic Eval …
Genetic Disorders with Predisposition to Paediatric Haematopoietic Malignancies-A Review.
Filipiuk A, Kozakiewicz A, Kośmider K, Lejman M, Zawitkowska J. Filipiuk A, et al. Cancers (Basel). 2022 Jul 22;14(15):3569. doi: 10.3390/cancers14153569. Cancers (Basel). 2022. PMID: 35892827 Free PMC article. Review.
Paediatricians should be aware of specific symptoms, which highlight the need of evaluation for cancer syndromes. The quickest possible identification of such syndromes is of key importance, due to the possibility of early detection of neoplasms, followed by presymptoma …
Paediatricians should be aware of specific symptoms, which highlight the need of evaluation for cancer syndromes. The quickest possib …
Association of TLR4 with Alzheimer's disease risk and presymptomatic biomarkers of inflammation.
Miron J, Picard C, Lafaille-Magnan MÉ, Savard M, Labonté A, Breitner J, Rosa-Neto P, Auld D, Poirier J; PREVENT-AD research group. Miron J, et al. Alzheimers Dement. 2019 Jul;15(7):951-960. doi: 10.1016/j.jalz.2019.03.012. Epub 2019 Jun 4. Alzheimers Dement. 2019. PMID: 31175027
INTRODUCTION: A coding variant in the TLR4 receptor (rs4986790), previously associated with longevity and Alzheimer's disease (AD) risk reduction, was examined in a population isolate (Quebec Founder Population [QFP]) and in presymptomatic individuals with a parental histo …
INTRODUCTION: A coding variant in the TLR4 receptor (rs4986790), previously associated with longevity and Alzheimer's disease (AD) risk redu …
Emerging therapies and challenges in spinal muscular atrophy.
Farrar MA, Park SB, Vucic S, Carey KA, Turner BJ, Gillingwater TH, Swoboda KJ, Kiernan MC. Farrar MA, et al. Ann Neurol. 2017 Mar;81(3):355-368. doi: 10.1002/ana.24864. Epub 2017 Feb 17. Ann Neurol. 2017. PMID: 28026041 Free PMC article. Review.
The development of disease-modifying therapies will necessitate monitoring programs to determine the long-term impact, careful evaluation of combined treatments, and further acceleration of improvements in supportive care. In advance of upcoming clinical trial results, we …
The development of disease-modifying therapies will necessitate monitoring programs to determine the long-term impact, careful evaluation …
139 results