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PHD1 regulates p53-mediated colorectal cancer chemoresistance.
Deschoemaeker S, Di Conza G, Lilla S, Martín-Pérez R, Mennerich D, Boon L, Hendrikx S, Maddocks OD, Marx C, Radhakrishnan P, Prenen H, Schneider M, Myllyharju J, Kietzmann T, Vousden KH, Zanivan S, Mazzone M. Deschoemaeker S, et al. Among authors: prenen h. EMBO Mol Med. 2015 Oct;7(10):1350-65. doi: 10.15252/emmm.201505492. EMBO Mol Med. 2015. PMID: 26290450 Free PMC article.
Overcoming resistance to antiangiogenic therapies.
Tejpar S, Prenen H, Mazzone M. Tejpar S, et al. Among authors: prenen h. Oncologist. 2012;17(8):1039-50. doi: 10.1634/theoncologist.2012-0068. Epub 2012 Jul 6. Oncologist. 2012. PMID: 22773560 Free PMC article. Review.
Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer.
Hamm A, Prenen H, Van Delm W, Di Matteo M, Wenes M, Delamarre E, Schmidt T, Weitz J, Sarmiento R, Dezi A, Gasparini G, Rothé F, Schmitz R, D'Hoore A, Iserentant H, Hendlisz A, Mazzone M. Hamm A, et al. Among authors: prenen h. Gut. 2016 Jun;65(6):990-1000. doi: 10.1136/gutjnl-2014-308988. Epub 2015 Mar 26. Gut. 2016. PMID: 25814648
MET is required for the recruitment of anti-tumoural neutrophils.
Finisguerra V, Di Conza G, Di Matteo M, Serneels J, Costa S, Thompson AA, Wauters E, Walmsley S, Prenen H, Granot Z, Casazza A, Mazzone M. Finisguerra V, et al. Among authors: prenen h. Nature. 2015 Jun 18;522(7556):349-53. doi: 10.1038/nature14407. Epub 2015 May 18. Nature. 2015. PMID: 25985180 Free PMC article.
Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis.
Wenes M, Shang M, Di Matteo M, Goveia J, Martín-Pérez R, Serneels J, Prenen H, Ghesquière B, Carmeliet P, Mazzone M. Wenes M, et al. Among authors: prenen h. Cell Metab. 2016 Nov 8;24(5):701-715. doi: 10.1016/j.cmet.2016.09.008. Epub 2016 Oct 20. Cell Metab. 2016. PMID: 27773694 Free article.
The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia.
Di Conza G, Trusso Cafarello S, Loroch S, Mennerich D, Deschoemaeker S, Di Matteo M, Ehling M, Gevaert K, Prenen H, Zahedi RP, Sickmann A, Kietzmann T, Moretti F, Mazzone M. Di Conza G, et al. Among authors: prenen h. Cell Rep. 2017 Feb 14;18(7):1699-1712. doi: 10.1016/j.celrep.2017.01.051. Cell Rep. 2017. PMID: 28199842 Free PMC article.
Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy.
Smeets D, Miller IS, O'Connor DP, Das S, Moran B, Boeckx B, Gaiser T, Betge J, Barat A, Klinger R, van Grieken NCT, Cremolini C, Prenen H, Mazzone M, Depreeuw J, Bacon O, Fender B, Brady J, Hennessy BT, McNamara DA, Kay E, Verheul HM, Maarten N, Gallagher WM, Murphy V, Prehn JHM, Koopman M, Punt CJA, Loupakis F, Ebert MPA, Ylstra B, Lambrechts D, Byrne AT. Smeets D, et al. Among authors: prenen h. Nat Commun. 2018 Oct 5;9(1):4112. doi: 10.1038/s41467-018-06567-6. Nat Commun. 2018. PMID: 30291241 Free PMC article.
171 results