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Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
Romagnoli R, Prencipe F, Oliva P, Kimatrai Salvador M, Brancale A, Ferla S, Hamel E, Viola G, Bortolozzi R, Persoons L, Balzarini J, Liekens S, Schols D. Romagnoli R, et al. Among authors: prencipe f. Bioorg Chem. 2020 Apr;97:103665. doi: 10.1016/j.bioorg.2020.103665. Epub 2020 Feb 18. Bioorg Chem. 2020. PMID: 32086053 Free article.
3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
Romagnoli R, Prencipe F, Oliva P, Baraldi S, Baraldi PG, Brancale A, Ferla S, Hamel E, Bortolozzi R, Viola G. Romagnoli R, et al. Among authors: prencipe f. Bioorg Chem. 2018 Oct;80:361-374. doi: 10.1016/j.bioorg.2018.06.037. Epub 2018 Jun 30. Bioorg Chem. 2018. PMID: 29986184 Free article.
Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold.
Romagnoli R, Prencipe F, Oliva P, Cacciari B, Balzarini J, Liekens S, Hamel E, Brancale A, Ferla S, Manfredini S, Zurlo M, Finotti A, Gambari R. Romagnoli R, et al. Among authors: prencipe f. Molecules. 2020 Apr 7;25(7):1690. doi: 10.3390/molecules25071690. Molecules. 2020. PMID: 32272719 Free PMC article.
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.
Romagnoli R, Baraldi PG, Salvador MK, Prencipe F, Lopez-Cara C, Schiaffino Ortega S, Brancale A, Hamel E, Castagliuolo I, Mitola S, Ronca R, Bortolozzi R, Porcù E, Basso G, Viola G. Romagnoli R, et al. Among authors: prencipe f. J Med Chem. 2015 Apr 9;58(7):3209-22. doi: 10.1021/acs.jmedchem.5b00155. Epub 2015 Mar 26. J Med Chem. 2015. PMID: 25785605 Free PMC article.
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors.
Romagnoli R, Prencipe F, Oliva P, Baraldi S, Baraldi PG, Schiaffino Ortega S, Chayah M, Kimatrai Salvador M, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Mattiuzzo E, Viola G. Romagnoli R, et al. Among authors: prencipe f. J Med Chem. 2019 Feb 14;62(3):1274-1290. doi: 10.1021/acs.jmedchem.8b01391. Epub 2019 Jan 18. J Med Chem. 2019. PMID: 30633509 Free article.
37 results