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Efficient soluble expression of active recombinant human cyclin A2 mediated by E. coli molecular chaperones.
Protein Expr Purif. 2015 Sep;113:8-16. doi: 10.1016/j.pep.2015.01.013. Epub 2015 May 6.
Protein Expr Purif. 2015.
PMID: 25956535
Free PMC article.
Iterative conversion of cyclin binding groove peptides into druglike CDK inhibitors with antitumor activity.
Premnath PN, Craig SN, Liu S, Anderson EL, Grigoroudis AI, Kontopidis G, Perkins TL, Wyatt MD, Pittman DL, McInnes C.
Premnath PN, et al.
J Med Chem. 2015 Jan 8;58(1):433-42. doi: 10.1021/jm5015023. Epub 2014 Dec 17.
J Med Chem. 2015.
PMID: 25454794
Free PMC article.
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Optimization of non-ATP competitive CDK/cyclin groove inhibitors through REPLACE-mediated fragment assembly.
Liu S, Premnath PN, Bolger JK, Perkins TL, Kirkland LO, Kontopidis G, McInnes C.
Liu S, et al. Among authors: premnath pn.
J Med Chem. 2013 Feb 28;56(4):1573-82. doi: 10.1021/jm3013882. Epub 2013 Feb 12.
J Med Chem. 2013.
PMID: 23323521
Free PMC article.
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Fragment based discovery of arginine isosteres through REPLACE: towards non-ATP competitive CDK inhibitors.
Premnath PN, Liu S, Perkins T, Abbott J, Anderson E, McInnes C.
Premnath PN, et al.
Bioorg Med Chem. 2014 Jan 1;22(1):616-22. doi: 10.1016/j.bmc.2013.10.039. Epub 2013 Nov 7.
Bioorg Med Chem. 2014.
PMID: 24286762
Free PMC article.
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Benzamide capped peptidomimetics as non-ATP competitive inhibitors of CDK2 using the REPLACE strategy.
Premnath PN, Craig SN, Liu S, McInnes C.
Premnath PN, et al.
Bioorg Med Chem Lett. 2016 Aug 1;26(15):3754-60. doi: 10.1016/j.bmcl.2016.05.067. Epub 2016 Jun 10.
Bioorg Med Chem Lett. 2016.
PMID: 27297568
Free PMC article.
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Structural and functional analysis of cyclin D1 reveals p27 and substrate inhibitor binding requirements.
Liu S, Bolger JK, Kirkland LO, Premnath PN, McInnes C.
Liu S, et al. Among authors: premnath pn.
ACS Chem Biol. 2010 Dec 17;5(12):1169-82. doi: 10.1021/cb1001262. Epub 2010 Oct 14.
ACS Chem Biol. 2010.
PMID: 20843055
Free PMC article.
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Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus.
Liu Y, Lightfoot YL, Seto N, Carmona-Rivera C, Moore E, Goel R, O'Neil L, Mistry P, Hoffmann V, Mondal S, Premnath PN, Gribbons K, Dell'Orso S, Jiang K, Thompson PR, Sun HW, Coonrod SA, Kaplan MJ.
Liu Y, et al. Among authors: premnath pn.
JCI Insight. 2018 Dec 6;3(23):e124729. doi: 10.1172/jci.insight.124729.
JCI Insight. 2018.
PMID: 30518690
Free PMC article.
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